How HIV-1 overcomes the person’s defenses and infects their cells has been studied intensively for over 30 years. While much has been learned, there remain events in the viral life … Continue Reading Researchers reveal and image new phase of HIV infection for the first time.
As a part of the human immune system, white blood cells create a number of enzymes that help fight disease. Sometimes, these enzymes can malfunction, causing damage to the body … Continue Reading Study sheds light on cancer-spreading enzymes produced by the immune-system.
A primary function of cytokines is to initiate immune responses; however, it has become increasingly apparent that they play major roles in the regulation of energy homeostasis, implicating them in … Continue Reading Sensor protein shown to have dual role in immune-system and metabolism.
B lymphocytes, also known as B cells, are the only cells to produce antibodies, which the immune system needs to fight off foreign intruders like pathogens in order to protect … Continue Reading Researchers identify previously unknown protein in immune cells.
Asthma rates have increased dramatically since the 1950s and now affect up to 20 per cent of children in western countries. In children ages 5-14 years, the rate of death … Continue Reading Four gut bacteria shown to decrease asthma risk in infants, validate probiotic treatment.
Sickle cell disease is inherited. It primarily affects people of African descent, including about one in every 500 African Americans born in the U.S. The defect causes the oxygen-carrying red … Continue Reading Researchers validate non-chemotherapy based cure for sickle cell in adults.
Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on health, leading to reduced life expectancy and … Continue Reading Researchers link obesity to a faulty immune system in animal model.
Tumours are known to evade the immune system by a variety of mechanisms, one of which is the recruitment of ‘myeloid-derived suppressor cells’ (MDSC). MDSCs suppress the ability of the … Continue Reading Researchers uncover more about the elusive pericyte-tumour interaction.
Premature birth is the birth of a baby at less than 37 weeks gestational age. Risk factors include diabetes, high blood pressure, being pregnant with more than one baby, being … Continue Reading Researchers identify a molecule which prevents preterm birth/labour.
Inflammatory bowel disease (IBD) is a painful, chronic inflammation of the gastrointestinal tract, affecting roughly two million children and adults in the U.S. Inflammatory bowel disease (IBD) beginning in childhood tends … Continue Reading Study identifies gene variants in inflammatory bowel disease under Age 5.
A main barrier to immune therapy success has been the tumour’s ability to keep the immune system from functioning against the cancer. The immune cells are there, however, like an … Continue Reading Researchers use ‘demethylating’ precision medicine to fight cancer.
To be activated, T cells must first recognize an antigen, receive appropriate costimulatory signals, and then encounter inflammatory cytokines to expand the immune response. This immune response has been harnessed … Continue Reading New T-cell regulation discovery set to rewrite immunology text books.
The immune system is a system of many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety … Continue Reading In world’s first, immune cells imaged responding to infection at the same time.
The immune system not only responds to infections and other potentially problematic abnormalities in the body, it also contains a built-in brake in the form of regulatory T cells. These … Continue Reading Researchers identify a previously unknown regulator of the immune system.
To combat pathogens, the immune system has developed various mechanisms to detect, defend against and even destroy micro-organisms that are harmful to the body. This includes antimicrobial peptides and natural … Continue Reading International team identifies bacteria which protect against type 1 diabetes.
The mucus barrier protects foreign materials and bacteria from entering and/or infecting lungs. In healthy lungs, inhaled matter is typically trapped in airway mucus and subsequently swept away from the … Continue Reading Researchers successfully bypass the mucus barrier in lungs for the first time.