There has been much focus on how to prevent heart disease by regulating the secretion of very low density lipoproteins (VLDL) by the liver. These lipoproteins are known to increase … Continue Reading Study shows damage to previously unknown liver protein leads to heart disease, fatty liver.
More than 600,000 patients in the United States alone suffer from end-stage liver disease, or cirrhosis. The only available cure is liver transplantation, but the shortage of donor livers means … Continue Reading New approach repairs living liver from within with no need of cell transplants.
Obesity has become a major health threat, affecting more than half a billion people worldwide in 2014. In particular, obesity increases the risk for insulin resistance, hypertension, coronary heart disease … Continue Reading Epigenetic modification which raises obesity risk and predicts fatty liver identified.
Tails in lizards and arms in starfish show an astounding ability to regrow, however, mammals have partially lost the capacity to extensively regenerate body parts. The liver is unique among … Continue Reading Researchers use epigenetic mechanism to regenerate mammalian liver.
In the UK liver disease has risen sharply over the past few decades and is the third biggest cause of premature mortality, with three quarters of liver deaths due to … Continue Reading Human study identifies definitive biomarker for liver disease breath test.
Telomere dysfunction is identified as origin of liver diseases such as chronic hepatitis and cirrhosis.
Telomeres are DNA regions at the ends of chromosomes that protect the genetic data of cells, preventing mutations and alterations in the DNA that could potentially cause disease. Telomeres shorten … Continue Reading Telomere dysfunction is identified as origin of liver diseases such as chronic hepatitis and cirrhosis.
Researchers at the University of Alberta and Beijing Genomics Institute have found that human betaretrovirus (HBRV) infection is commonly observed in the cells of patients with primary biliary cirrhosis (PBC), a … Continue Reading Researchers solve 40-year-old mystery of betaretrovirus infection in humans.
The power plants that fuel liver cells rapidly splinter when exposed to bile salts that aid digestion, prompting cell death, but blocking this excessive fission appears to protect the liver, … Continue Reading Controlling mitochondria cell-division reduces liver cell death in cholestasis.