Ten million Canadians are living with diabetes or pre-diabetes. The Canadian Diabetes Association reports that more than 20 Canadians are newly diagnosed with the disease every hour of every day. … Continue Reading New mitochondria-based insulin amplifier pathway identified in T2 diabetes.
Synaptic mitochondria are thought to be critical in supporting neuronal energy requirements at the synapse, and bioenergetic failure at the synapse may impair neural transmission and contribute to neurodegeneration. However, … Continue Reading Researchers link impaired mitochondria and a loss of ATP to neurodegeneration.
High blood sugar is a defining characteristic of Type 2 diabetes and the cause of many of the condition’s complications, including kidney failure, heart disease, and blindness. Most diabetes medications … Continue Reading Researchers block mitochondrial glucose production to treat type 2 diabetes in preclinical trials.
In human cells, shortened telomeres, the protective caps at the ends of chromosomes, are both a sign of aging and contribute to it. The effects of chronic diseases such as … Continue Reading Researchers use dietary supplement in atherosclerotic mice to lengthen telomeres.
A healthy motor neuron needs to transport its damaged components from the nerve-muscle connection all the way back to the cell body in the spinal cord. If not, the defective … Continue Reading Researchers identify the role mitochondria plays in familial ALS.
Free radicals are especially reactive atoms or groups of atoms that have one or more unpaired electrons. They are produced in the body as a by-product of normal metabolism and … Continue Reading New findings on the free radical theory of aging and mitochondrial damage.
Impaired activation of mitochondrial energy metabolism in the presence of glucose has been demonstrated in pancreatic beta-cells from patients with type 2 diabetes. The cause of this dysfunction has been … Continue Reading New diagnostic identifies mitochondria dysfunction in Type 2 diabetes.
The benefits of exercise are well known, but physical fitness becomes increasingly difficult as people age or develop ailments, creating a downward spiral into poor health. Now, researchers at Duke … Continue Reading Study identifies diet supplement which boosts muscle stamina via mitochondria in animal studies.
The retina is a layer of tissue in the back of the eye that converts light into nerve impulses. The retina contains small, specialized neurons called bipolar cells that transmit … Continue Reading Researchers discover previously uncharted part of the eye.
In a life-threatening situation, the heart beats faster and harder, invigorated by the fight-or-flight response, which instantaneously prepares a person to react or run. Now, a new study by researchers … Continue Reading Researchers map how calcium uptake in mitochondria during a heart attack causes large cell death.
Researchers have long wondered what causes people to lose muscle strength as they age and how exercise can prevent it from happening. Now, McMaster University researchers have discovered a key … Continue Reading Researchers identify protein required to maintain muscle mass and strength during aging.
Scientists from the Institut Pasteur, CNRS, Institut Gustave Roussy and CEA, have succeeded in restoring normal activity in cells isolated from patients with the premature aging disease Cockayne syndrome. They … Continue Reading Researchers identify and correct premature aging in diseased cells.
OvaScience, a global fertility company focused on the discovery, development and commercialization of new treatment options, announced that the world’s first augmented baby has been born in Canada. Now, researchers … Continue Reading New IVF technique deemed successful as world’s first ‘augmented’ baby is born.
A group of researchers from the Lomonosov Moscow State University and the University College Cork have studied the early response of cells to ischemia, which is a restriction in blood … Continue Reading Researchers identify previously unseen mechanisms of the early response of cells to ischemia.
Mitochondrial diseases are maternally inherited genetic disorders that cause a wide spectrum of debilitating conditions and which currently have no cure. In a new opensource study published in the journal … Continue Reading Researchers successfully ‘edit’ mitochondrial DNA to prevent inherited disease in animal model.
Just as some people seem built to run marathons and have an easier time going for miles without tiring, others are born with a knack for memorizing things, from times … Continue Reading Researchers identify protein responsible for ‘enhancing’ learning and memory.