When it comes to hearing, precision is important say researchers. Due to the fact vertebrates, such as birds and humans, have two ears, and sound-waves from either side travel different … Continue Reading Researchers map auditory brain cells for maximum hearing precision.
The decision to engage in food-seeking behaviour depends on homeostatic signals relating to energy balance and the presence of competing motivational drives, as well as learned brain cues signaling food … Continue Reading Neuroimaging shows the effect of hunger on the brain’s response to food cues.
Alcoholism is a chronic relapsing disorder associated with compulsive drinking, loss of control over intake, and emergence of a negative emotional state during abstinence from the drug. Special emphasis has … Continue Reading Researchers target neurons involved in compulsive drinking to reverse alcohol dependence in rats.
In roughly 20 million people with drug-resistant epilepsy, focal seizures originating in dysfunctional brain networks will often evolve and spread to surrounding tissue, disrupting function in otherwise normal brain regions. … Continue Reading Study identifies the brain network that controls the spread of epileptic seizures.
Think about a person performing a simple action, when they reach for a pan of brownies, a ball-shaped brain structure called the striatum is critical for controlling their movement toward … Continue Reading New map of the brain’s action centre upends textbook theory.
Epigenetic dysfunction is implicated in many neurological and psychiatric diseases, including Alzheimer’s disease and schizophrenia. Consequently, histone deacetylases (HDACs) are being aggressively pursued as therapeutic targets. However, a fundamental knowledge … Continue Reading Researchers image the epigenetics of the human brain for the first time ever.
Understanding the integrative role of the central nervous system in the prevalence of obesity and obesity-related diseases is of great importance. It has been hypothesized that flexibility of food reward–related … Continue Reading Neuroimaging shows that response to food cues differ in severely obese women.
Alzheimer’s disease (AD) is common and highly heritable with many gene variants associated with it. However, the genetic risk for AD have not been clearly delineated, with the stage of … Continue Reading Study identifies a genetic risk score for Alzheimer’s disease in young adults.
In alcoholism and addictive drugs repeated exposure triggers glutamatergic and GABAergic plasticity in many neuronal populations. The dorsomedial striatum (DMS), a brain region critically involved in addiction, contains medium spiny … Continue Reading Researchers identify and successfully activate neurons that tell the brain to stop drinking.
Delayed deterioration of neurological function after ischemia stroke is a well-documented clinical problem. However, minimal studies exist pertaining to spinal cord blood flow and blood-spinal cord barrier (BSCB) integrity with … Continue Reading Study maps how a stroke damages the blood-spinal cord barrier.
Performance of cognitive tasks requires reallocation of resources within and among cortical networks. Understanding the molecular mechanisms that govern such network dynamics is a longstanding goal of cognitive neuroscience. A … Continue Reading Neuroimaging maps interaction between neural networks during working memory.
The blood-brain barrier (BBB), a collection of cells and subcellular structures in the cerebrovascular wall that separates the circulating blood from the brain, is essential to keep brain tissue in … Continue Reading Leakages identified in the blood-brain barrier of patients with early Alzheimer’s disease.
When the nervous system is developing neurons send their axons, the parts of neurons that make up the body’s nerves, to make connections with other neurons. For instance, a neuron in … Continue Reading Researchers identify protein complex that helps direct growth of axons.
The hippocampus is a critical structure for encoding of novel experiences. A particularly compelling puzzle is how the hippocampus encodes new information in the presence of interference from past memories. … Continue Reading Neuroimaging shows how the brain switches from past to present memory mode.
Twenty-years ago there was a big step forward in the understanding of obesity when researchers discovered that a person’s appetite is controlled by a key molecule called leptin. Leptin is … Continue Reading Glia brain cells implicated in appetite control.
Memories are formed at structures in the brain known as dendritic spines which communicate with other brain cells via synapses. It is known that the number of these brain connections … Continue Reading Study identifies cause of dendritic pruning defect linked to autism and schizophrenia.