Category Archives: neurofibrillary tangles

Researchers investigate how form affects function and aggregation of tau protein in the brain.

A unique class of proteins in the human body has the ability to alter their configuration. These so-named intrinsically disordered proteins (IDPs) lack a fixed or ordered three-dimensional structure, which can be influenced by exposure to various chemicals and cellular modifications. A new study by a team from UC Santa Barbara looked at a particular IDP called tau, which plays

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