Category Archives: pancreatic beta cell

Researchers identify microtubule mechanism and role in insulin secretion.

Glucose-stimulated insulin secretion (GSIS) in pancreatic beta cells maintains glucose homeostasis and prevents diabetes. Despite decades of studies, knowledge about what controls the precise amount of insulin release on a given stimulus is incomplete.  Now, a study from researchers at Vanderbilt University has shown that microtubules act as a cellular potentiometer to precisely control insulin secretion and suggest that disturbance

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