Alzheimer’s is the most common form of dementia globally and affects up to 40,000 people in Ireland today. It is the fourth leading cause of death in individuals over the … Continue Reading Researchers have discovered clearance of Alzheimer’s protein across the blood-brain barrier.
More than five million Americans are living with Alzheimer’s disease (AD). Of them, 400,000 also have Down syndrome. People with Down syndrome (DS) represent the world’s largest population of predetermined … Continue Reading Study validates beta amyloid as cause of dementia in both Alzheimer’s and Down syndrome.
It has been known for some years that Alzheimer’s disease is characterised by two types of lesions, amyloid plaques and degenerated tau protein. The amyloid component and altered cholesterol metabolism … Continue Reading Study shows link between the tau component of Alzheimer’s and cholesterol.
Today, more than 5.1 million Americans live with Alzheimer’s disease, a devastating type of dementia that plagues memory and thinking. That number is expected to triple in the coming decades. … Continue Reading Work begins on turning an ApoE4 Alzheimer’s brain into an ApoE2 Alzheimer’s brain.
Researchers identify protein in the brain which inhibits key enzyme implicated in Alzheimer’s disease.
The need for a new approach to treatment of Alzheimer’s disease is urgent. Alzheimer’s is the most common age-related dementia and the number of cases in the United States is … Continue Reading Researchers identify protein in the brain which inhibits key enzyme implicated in Alzheimer’s disease.
Examining post-mortem tissue from the brains of people with Alzheimer’s disease, Stanford University researchers state they have identified what appear to be iron-containing microglia, specialized scavenger cells that sometimes become … Continue Reading A human study identifies region specific iron-containing microglia in Alzheimer’s brains.
Through studying brain scans and cerebrospinal fluid of healthy adults researchers at Washington University have shown that changes in key biomarkers of Alzheimer’s disease during midlife can help identify those who … Continue Reading First ever large-scale human study validates multiple biomarkers for Alzheimer’s disease.
Researchers at the University of Kentucky have completed a study that revealed differences in the way neuroinflammation, considered a key component of Alzheimer’s disease, is expressed in different subsets of … Continue Reading Study finds Alzheimer’s disease presents differently in patients with Down syndrome.
Alzheimer’s disease is the most common form of dementia, affecting over 44 million people worldwide. Inside the brain, Alzheimer’s disease is characterized by loss of neurons, and presence of abnormal … Continue Reading Protein involved in Alzheimer’s proven to have a role in weakening synaptic plasticity.
Degeneration of the white matter of the brain may be an early marker of specific types of Alzheimer’s disease (AD), including early-onset AD, according to results of a new study … Continue Reading Researchers identify specific types of Alzheimer’s disease using white matter neuroimaging test.
Researchers have uncovered a unique connection between diabetes and Alzheimer’s disease, providing further evidence that a disease that robs people of their memories may be affected by elevated blood sugar, … Continue Reading Scientists find new link between diabetes and Alzheimer’s disease.
After six years of painstaking research, a UCLA-led team has validated the first standardized protocol for measuring one of the earliest signs of Alzheimer’s disease, the atrophy of the part … Continue Reading Harmonized neuroimaging protocol for measuring early sign of Alzheimer’s has been developed.
Brain levels of the lipid ceramide are high in Alzheimer’s disease, and now scientists have found increased levels of an antibody to the lipid in their disease model. While some … Continue Reading New study provides more proof that Alzheimer’s is an autoimmune disease.
A study from researchers at Massachusetts General Hospital (MGH) and Brigham and Women’s Hospital (BWH) reveals for the first time exactly how mutations associated with the most common form of … Continue Reading Study identifies the epigenetic pathway of familial Alzheimer’s disease.
Amyloid, an abnormal protein whose accumulation in the brain is a hallmark of Alzheimer’s disease, starts accumulating inside neurons of people as young as 20, a much younger age than … Continue Reading Alzheimer amyloid accumulation found in young adult brains for the first time.
Research suggests anti-inflammatory protein, interleukin 10, may trigger plaque in Alzheimer’s disease.
Inflammation has long been studied in Alzheimer’s, but in a counterintuitive finding, University of Florida researchers have uncovered the mechanism by which anti-inflammatory processes may trigger the disease. This anti-inflammatory … Continue Reading Research suggests anti-inflammatory protein, interleukin 10, may trigger plaque in Alzheimer’s disease.