The onset of ALS, also known as Lou Gehrig’s disease, is marked by the gradual degradation and eventual death of neuronal axons, the slender projections on nerve cells which transmit … Continue Reading Researchers identify the key instigator of neuron damage in sporadic and inherited ALS.
It is known that Amyotrophic Lateral Sclerosis (ALS) gradually kills nerve cells in the brain and spinal cord. It is one of the most prevalent neuromuscular diseases, resulting in more … Continue Reading Study shows microglia has a direct role in the development of Lou Gehrig’s disease.
Amyotrophic lateral sclerosis (ALS) is the most common neurodegenerative disease affecting motor neurons. This fatal disease is characterized by progressive muscular atrophy and doesn’t have an effective treatment. Patients with … Continue Reading Study provides first definitive evidence and description of protein clump toxicity in ALS.
A healthy motor neuron needs to transport its damaged components from the nerve-muscle connection all the way back to the cell body in the spinal cord. If not, the defective … Continue Reading Researchers identify the role mitochondria plays in familial ALS.
Almost a decade ago scientists first described the clumps of TDP-43 that commonly appear in the degenerated brain or nerve cells of those with FTD or ALS. However, whether the … Continue Reading Researchers identify the mechanism of protein clumps in the brain of patients with ALS.
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive, invariably fatal neurological disease that attacks the nerve cells responsible for controlling voluntary muscles. The disease doesn’t usually impair a person’s mind … Continue Reading New details uncovered about the genetic cause of ALS.
Scientists from the Gladstone Institutes and the University of Michigan have identified a cellular mechanism that can be targeted to treat ALS. The researchers discovered that increasing levels of a … Continue Reading Researchers identify previously unknown neuroprotective pathway in ALS.
Researchers at the University of Toronto have uncovered new insights on the genetic causes of Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s disease. These findings could uncover a … Continue Reading Human generational study pinpoints epigenetic cause of Amyotrophic Lateral Sclerosis (ALS).
Researchers from the University of Wisconsin have developed a unique model for learning more about the role of human astrocytes. The findings may lay a foundation for the treatment of … Continue Reading Researchers grow human astrocytes in situ for the first time for potential ALS cure.
For the first time, scientists have revealed a mechanism underlying the cellular degeneration of upper motor neurons, a small group of neurons in the brain recently shown to play a … Continue Reading Researchers identify mechanism of upper motor neuron degeneration in Amyotrophic Lateral Sclerosis.
Genetics may play a larger role in causing Lou Gehrig’s disease than previously believed, potentially accounting for more than one-third of all cases, according to one of the most comprehensive … Continue Reading New neurogenetic origins of Lou Gehrig’s disease uncovered.
Lou Gehrig’s disease, also known as amyotrophic lateral sclerosis, or ALS, might damage muscle-controlling nerve cells in the brain earlier in the disease process than previously known, according to research … Continue Reading New point of origin identified for Amyotrophic Lateral Sclerosis (ALS).
Using a technique that illuminates subtle changes in individual proteins, chemistry researchers at Cornell and Scripps Research Institute have uncovered new insight into the underlying causes of Amyotrophic Lateral Sclerosis (ALS). … Continue Reading Cornell scientists show that ALS is a protein aggregation disease.