It is known that the loss or dysfunction of islet β cells in the pancreas results in an imbalance in blood glucose homeostasis, leading to the development of type 2 … Continue Reading Researchers identify new links between nicotine and type 2 diabetes.
Diffuse gliomas represent 80% of all malignant brain tumours. Adult diffuse gliomas are classified and graded according to histological criteria. However, although histopathology classification is well established it suffers from unstandardized, … Continue Reading Large-scale study identifies new epigenetic subtypes of brain cancer.
It is known that the age-related growth differentiation factor 11 (GDF11) is member of the transforming growth factor β superfamily of proteins. Circulating GDF11 concentrations appear to decline with age, … Continue Reading Study identifies previously unknown molecular pathway in aging.
Colon cancer is one of the leading causes of cancer-related deaths worldwide, and researchers are hard at work to understand the disease’s complex molecular underpinnings. Now, a study from researchers … Continue Reading Newly identified gene pair in colon cancer challenges whole paradigm on causation.
It has been shown that patterns of poor nutritional intake may exacerbate the elevated morbidity experienced by cancer survivors. While most cancer patients in the United States are motivated to … Continue Reading Large-scale study investigates the diet quality of cancer survivors.
Chromosomal alterations and deletions are often observed in cancers. Recurrent genetic losses are thought to contribute to disease processes through deregulating critical cellular programs that govern proliferation and differentiation. However, … Continue Reading Researchers identify precision medicine, suppressor gene for acute myeloid leukemia.
Antigen receptor genes are assembled by controlled, large-scale deletions and inversions. Errors in this process, known as V(D)J recombination, produce aberrant genomic rearrangements, which can fuel the development of T- … Continue Reading Researchers identify points where incorrect immune cell DNA editing causes blood cancer.
DNA methylation is essential for the proper control of gene expression and cell identity, what enables cells with the same genetic material to become, for example, a nerve cell, a … Continue Reading Single-cell imaging developed which can record DNA methylation in real time.
More than five million Americans are living with Alzheimer’s disease (AD). Of them, 400,000 also have Down syndrome. People with Down syndrome (DS) represent the world’s largest population of predetermined … Continue Reading Study validates beta amyloid as cause of dementia in both Alzheimer’s and Down syndrome.
Tauopathies are neurodegenerative diseases that are signified by the presence of irregular tangle-like clumps of the protein tau that appear in the brain and accumulate during as the disease progresses. … Continue Reading Study identifies a previously unknown mechanism of neurofibrillary tangle formation.
Glaucoma is the leading cause of irreversible blindness worldwide and a growing public health concern because of an aging global population. It is often associated with increased fluid pressure in … Continue Reading Large-scale study finds link between blood levels of metals and glaucoma.
Type 1 diabetes is an autoimmune disease, which primarily surfaces in childhood, where the immune system attacks the insulin-producing cells of the pancreas, leaving children facing a lifetime of daily … Continue Reading Lower levels of four proteins crucial for immune response found in T1 diabetes patients.
The Centers for Disease Control and Prevention (CDC) is reporting on the discovery of a new virus that may have contributed to the death of a previously healthy man in … Continue Reading The CDC announces the discovery of a new virus.
Landmark study shows that early blood glucose control lengthens life in people with type 1 diabetes.
People with type 1 diabetes who intensively control their blood glucose (blood sugar) early in their disease are likely to live longer than those who do not, according to a … Continue Reading Landmark study shows that early blood glucose control lengthens life in people with type 1 diabetes.
The outbreak of the Ebola virus disease occurring in West Africa may have originated from contact between humans and virus-infected bats, suggests a study led by researchers from the Robert … Continue Reading Researchers investigate animal host for the origin of the West African Ebola epidemic.
The U.S. Food and Drug Administration (FDA) has cleared the EnLite Neonatal TREC Kit for the company PerkinElmer, the first screening test permitted to be marketed by FDA for Severe … Continue Reading The FDA clears the first-ever newborn test to detect Severe Combined Immunodeficiency.