Antidepressants are recommended as a first-line treatment of severe depression and for the treatment of mild-to-moderate depression that persists after conservative measures such as cognitive therapy.  Experts recommend against their routine use in those who have chronic health problems and mild depression.  Selective serotonin re-uptake inhibitors (SSRIs) are a recent class of compounds typically used as antidepressants in the treatment of major depressive disorder and … Continue reading Study maps structural brain changes caused by antidepressants.