Infectious diseases continue to affect and kill a multitude of people worldwide, with vaccination seen as the most powerful weapon against this threat. Vaccines are prepared from weakened forms of … Continue Reading Synthetic vaccine can be stored at warmer temperatures.
Cancer immunotherapy, which uses the body’s immune defenses to fight cancer, has transformed cancer treatment over the past decade, however, only a handful of solid tumors have responded to treatment, … Continue Reading Synthetic bacteria delivers nanobodies to kill cancer.
The Zika virus is a mosquito-borne disease designated a global public health concern, with more than two billion people at risk. For most people Zika manifests as a mild infection, … Continue Reading Synthetic antibody protects mice and monkeys from Zika.
The WHO recommends complete withdrawal of the oral polio vaccine (OPV) by April 2016 globally and replacing with at least one dose of inactivated poliovirus vaccine (IPV). However, high-cost, limited … Continue Reading Researchers develop plant-based Polio booster vaccine.
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired social communication and interaction, and restricted, repetitive patterns of behaviour. Approximately 1 in 70 children are diagnosed with ASD … Continue Reading Researchers identify new blood-based biomarker for boys with autism.
Towards a universal HIV vaccine with the identification of first immature ‘elite controller’ antibody.
HIV has been hard to beat as the virus mutates rapidly and has a sturdy set of defenses, including a ‘shield’ of glycan molecules on the surface of its envelope … Continue Reading Towards a universal HIV vaccine with the identification of first immature ‘elite controller’ antibody.
Envelope glycoprotein GP120 is a glycoprotein exposed on the surface of the HIV envelope (ENV). The envelope glycoprotein trimer is essential for HIV entry into cells as it plays a … Continue Reading New breakthrough imaging shows HIV structure in unprecedented detail.
In recent years, Ebola outbreaks have increased in frequency, duration, and geographical spread, underscoring the need for pre- and post-exposure treatments. Antibodies targeting the Ebola virus surface glycoprotein, the viral structure … Continue Reading Previously unknown ebola-fighting antibodies identified in outbreak survivor’s blood.
How HIV-1 overcomes the person’s defenses and infects their cells has been studied intensively for over 30 years. While much has been learned, there remain events in the viral life … Continue Reading Researchers reveal and image new phase of HIV infection for the first time.
B lymphocytes, also known as B cells, are the only cells to produce antibodies, which the immune system needs to fight off foreign intruders like pathogens in order to protect … Continue Reading Researchers identify previously unknown protein in immune cells.
Over the past three decades DNA has emerged as an exceptional molecular building block for nanoconstruction due to its predictable conformation and programmable base-pairing interactions. DNA nanotechnology is the design … Continue Reading Low-cost DNA nanobot can detect many diseases, including HIV.
MERS is caused by an emerging human coronavirus, which is distinct from the SARS coronavirus. Since its identification in 2012, MERS has been linked to over 1,300 infections and close … Continue Reading New synthetic-DNA vaccine protects against MERS in simian model.
Type 1 diabetes is an autoimmune disease, which primarily surfaces in childhood, where the immune system attacks the insulin-producing cells of the pancreas, leaving children facing a lifetime of daily … Continue Reading Lower levels of four proteins crucial for immune response found in T1 diabetes patients.
A research team from Duke-NUS, Vanderbilt University, the University of North Carolina and the University of California, Berkeley has found the second-to-last piece of the puzzle needed to potentially cure or … Continue Reading Researchers identify the elusive antibody that zaps resilient dengue serotype 2.
New technology developed by Howard Hughes Medical Institute (HHMI) and Brigham and Women’s Hospital researchers makes it possible to test for current and past infections with any known human virus by … Continue Reading New bacteriophage-based assay gives a person’s whole viral infection history in a drop of blood.
In a report on what is believed to be the first small clinical trial of its kind, researchers at the Johns Hopkins Kimmel Cancer Center say they have safely used … Continue Reading Researchers safely use immune cells to treat multiple myeloma in human trials.