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Tagastrocyte

Researchers identify how the blood-brain barrier is maintained to control ‘tight junction’ function.

It has long been known that the brain is protected from alterations elsewhere in the body by a highly regulated gateway known as the blood-brain barrier, which allows only selected … Continue Reading Researchers identify how the blood-brain barrier is maintained to control ‘tight junction’ function.

Selective mitochondrial chemotherapy, decimates brain tumours and headed for human trials.

An experimental drug that attacks brain tumour tissue by crippling the cells’ energy source called the mitochondria has passed early tests in animal models and human tissue cultures, state researchers … Continue Reading Selective mitochondrial chemotherapy, decimates brain tumours and headed for human trials.

Neuroimaging study finds first evidence of neuroinflammation in brains of chronic pain patients.

A new study from Massachusetts General Hospital (MGH) researchers has found, for the first time, evidence of neuroinflammation in key regions of the brains of patients with chronic pain. By … Continue Reading Neuroimaging study finds first evidence of neuroinflammation in brains of chronic pain patients.

Discovery of new drug targets for memory impairment in Alzheimer’s Disease.

Discovery of new drug targets for memory impairment in Alzheimer’s Disease. A study from KIST has revealed the novel mechanism of how Alzheimer’s patients might lose their memory. The researchers also propose new therapeutic targets, which include GABA production and release mechanisms in reactive astrocytes for treatment of Alzheimer’s disease. Furthermore, we provide a stepping stone for the development of MAO-B inhibitors with long lasting efficacy.

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