To be activated, T cells must first recognize an antigen, receive appropriate costimulatory signals, and then encounter inflammatory cytokines to expand the immune response. This immune response has been harnessed via immunotherapies, treatment that uses certain parts of a person’s immune system to fight diseases such as cancer.  It has been somewhat of a mystery as to how some of these immunotherapies have been shown to … Continue reading New T-cell regulation discovery set to rewrite immunology text books.