Genetic susceptibility is thought to play a role in common diseases including those affecting the colon such as inflammatory bowel diseases (IBD) and colorectal cancer. As is the case for … Continue Reading Study shows how gut microbiota interact with genes to promote Crohn’s disease.
Allergies are characterized by inappropriate inflammatory responses to benign environmental antigens. Primary clinical approaches to allergic disease consist of symptom control or administration of soluble antigens to skew the immune response … Continue Reading Novel nanoparticle acts like Trojan horse to halt asthma in animal model.
Systemic lupus erythematosus (SLE) is a common autoimmune disorder in which the body’s immune system mistakenly attacks healthy tissues, it can affect the skin, joints, kidneys, brain, and other organs. … Continue Reading Study shows how mitochondria drives autoimmune response in lupus.
Coeliac disease is a chronic, immunological disease that is manifested as intolerance to gluten proteins present in wheat, rye and barley. This intolerance leads to an inflammatory reaction in the … Continue Reading Gene crucial to the development of celiac disease found in ‘junk’ DNA.
The body has an army of millions of immune cells. These cells contain receptors generated through random genetic rearrangements, a clever strategy to keep them ready to fight unfamiliar viruses … Continue Reading Previously unknown immune cell identified, with implications for T1 diabetes.
The innate immune system is hard-wired to protect people from infection. However, mutations in these protective genes can lead to uncontrolled inflammation, resulting in autoinflammatory disease. Autoinflammatory diseases are characterized … Continue Reading Precision medicine study identifies decades-old mysterious, rare and debilitating disease.
It is known that Amyotrophic Lateral Sclerosis (ALS) gradually kills nerve cells in the brain and spinal cord. It is one of the most prevalent neuromuscular diseases, resulting in more … Continue Reading Study shows microglia has a direct role in the development of Lou Gehrig’s disease.
Psoriasis is a chronic autoimmune disorder that affects 2% of the world population. It is characterised by inflammation and scaling of the skin, accompanied by a greater risk of contracting … Continue Reading Researchers identify a link between psoriasis and bone loss.
It is known that HIV, the causative agent of AIDS, is severely species restricted, and, to date, only humans and chimpanzees have been shown to be susceptible to infection. Human … Continue Reading First-ever study proves HIV targets & replicates in human macrophages.
Type 1 diabetes is the autoimmune form of diabetes, in which insulin-producing beta cells in the pancreas are destroyed by immune cells, especially those known as T cells. Insulin is … Continue Reading Researchers identify previously unknown class of antigen present in T1 diabetes.
Thyroid disease affects about 12 percent of the U.S. population. While many people with thyroid disease don’t even know they have it, an overactive or underactive thyroid can cause a … Continue Reading Researchers identify mechanism which ‘turns thyroid on’.
Another year of growth for the Healthinnovations, many great breakthroughs, with previously immature technologies and disciplines coming into their own, as crucial parts of global innovation. For instance, biomarkers have … Continue Reading The Top Ten Healthinnovations of 2015.
Obesity increases risk of age-related cognitive decline and is accompanied by peripheral inflammation. Studies in rodent models of obesity have demonstrated that impaired hippocampal function correlates with microglial activation, however, … Continue Reading Study shows obesity causes microglia to start eating neural connections.
The intriguing relationship between metabolism and the immune system has been receiving increasing attention over the past few years. It is known that macrophages accumulate in adipose tissue during obesity. … Continue Reading Researchers identify immune cells that fight obesity in animal model.
Asthma rates have increased dramatically since the 1950s and now affect up to 20 per cent of children in western countries. In children ages 5-14 years, the rate of death … Continue Reading Four gut bacteria shown to decrease asthma risk in infants, validate probiotic treatment.
Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on health, leading to reduced life expectancy and … Continue Reading Researchers link obesity to a faulty immune system in animal model.