HIV has been hard to beat as the virus mutates rapidly and has a sturdy set of defenses, including a ‘shield’ of glycan molecules on the surface of its envelope … Continue Reading Towards a universal HIV vaccine with the identification of first immature ‘elite controller’ antibody.
An estimated 100,000 Canadians live with multiple sclerosis; there is currently no cure for the disease. Modern scientific understanding has considered multiple sclerosis (MS) to be a disease controlled by the … Continue Reading Specific subset of b-cell responsible for Multiple Sclerosis disease activity identified.
B lymphocytes, also known as B cells, are the only cells to produce antibodies, which the immune system needs to fight off foreign intruders like pathogens in order to protect … Continue Reading Researchers identify previously unknown protein in immune cells.
Antigen receptor genes are assembled by controlled, large-scale deletions and inversions. Errors in this process, known as V(D)J recombination, produce aberrant genomic rearrangements, which can fuel the development of T- … Continue Reading Researchers identify points where incorrect immune cell DNA editing causes blood cancer.
Practically everyone gets fatter as they get older, however, according to a new study from researchers at Duke University some people can blame their genes for the extra padding. The … Continue Reading Researchers identify gene responsible for obesity and diabetes in old age.
Natural killer cells of the immune system can fend off malignant lymphoma cells and thus are considered a promising therapeutic approach. However, previous studies show that in the direct vicinity … Continue Reading Researchers identify how lymphoma tumours evade the immune response.
An analysis of five families has revealed a previously unknown genetic immunodeficiency, says an international team led by researchers from Boston Children’s Hospital. The condition, linked to mutations in a … Continue Reading International team discovers previously unknown genetic immunodeficiency.
The bacteria that sneak past the brain’s defenses to cause deadly bacterial meningitis are clever adversaries. Bacteria use various molecular tricks bacteria use to convince their host that they are … Continue Reading Study identifies ‘molecular trick’ used by bacteria to bypass the blood-brain barrier.
About 15% of patients with Lyme disease develop peripheral and central nervous system involvement, often accompanied by debilitating and painful symptoms. Now, researchers from Tulane National Primate Research Center and Louisiana … Continue Reading Researchers map neuroinflammation and nervous system manifestations of Lyme disease.
Researchers from the Garvan Institute of Medical Research have discovered a new population of ‘memory’ immune cells, throwing light on what the body does when it sees a microbe for the … Continue Reading Researchers discover a new type of ‘memory’ immune cell.
In the ongoing Ebola outbreak in West Africa, whose death toll is approaching 10,000, little information has been available about how the human immune response unfolds after infection. Now, researchers … Continue Reading First look at hospitalized Ebola survivors’ immune cells finds no immunosuppression.
Scientists from the CNRS, INSERM and Université de Limoges have demonstrated that the production of type E immunoglobulins (IgE)2 by B lymphocytes induces a loss in their mobility and the … Continue Reading Researchers map programmed cell death in immune cells to prevent allergy.
Researchers from Institut d’Investigació Biomèdica de Bellvitge (IDIBELL) have established the epigenetic patterns of breast cancer and also its clinical consequences. The opensource study is published in the journal Molecular … Continue Reading New breast cancer classification based on epigenetics.