An ever-growing epidemic, obesity is a chronic medical condition where excess body fat has accumulated to the point it may cause a multitude of health disorders. Several studies have also … Continue Reading Visceral fat delivers a signal to the brain that impairs cognition.
Hypertension is a leading risk factor for dementia, however, the mechanisms underlying its damaging effects on the brain are poorly understood. Now, a study from researchers at Weill Cornell Medicine … Continue Reading Immune cells identified as the culprit linking hypertension and dementia.
The rapid rise in obesity and associated spread of type 2 diabetes represent an enormous challenge for society, with no efficient and safe medicines to prevent or stop this development … Continue Reading Astrocytes shown to control sugar in the brain, as well as neurons.
Delayed deterioration of neurological function after ischemia stroke is a well-documented clinical problem. However, minimal studies exist pertaining to spinal cord blood flow and blood-spinal cord barrier (BSCB) integrity with … Continue Reading Study maps how a stroke damages the blood-spinal cord barrier.
The blood-brain barrier (BBB), a collection of cells and subcellular structures in the cerebrovascular wall that separates the circulating blood from the brain, is essential to keep brain tissue in … Continue Reading Leakages identified in the blood-brain barrier of patients with early Alzheimer’s disease.
When the blood-brain barrier (BBB) is breached the brain becomes vulnerable to infection and injury. Therefore, it’s imperative that the openings in the BBB are resealed quickly. This most frequently … Continue Reading Researchers identify new role for microglia in blood-brain barrier maintainence.
Alzheimer’s is the most common form of dementia globally and affects up to 40,000 people in Ireland today. It is the fourth leading cause of death in individuals over the … Continue Reading Researchers have discovered clearance of Alzheimer’s protein across the blood-brain barrier.
The formation of the neurovascular unit, blood brain-barrier tracked in real-time for the first time.
Crucial bodily functions like heart rate, blood flow, breathing and digestion are regulated by the neurovascular unit. The neurovascular unit is made up of the blood–brain barrier, blood vessels, microglia … Continue Reading The formation of the neurovascular unit, blood brain-barrier tracked in real-time for the first time.
A drug that could halt the progression of multiple sclerosis may soon be developed thanks to a discovery by a team at the CHUM Research Centre and the University of … Continue Reading New treatment blocks progression of mutliple sclerosis in animal model.
The bacteria that sneak past the brain’s defenses to cause deadly bacterial meningitis are clever adversaries. Bacteria use various molecular tricks bacteria use to convince their host that they are … Continue Reading Study identifies ‘molecular trick’ used by bacteria to bypass the blood-brain barrier.
Researchers at the University of North Carolina have used exosomes, tiny bubbles of protein and fat produced naturally by cells, to bypass the body’s defenses and deliver a potent antioxidant … Continue Reading Researchers utilize natural exosomes to deliver Parkinson’s treatment directly to brain.
Researchers identify how the blood-brain barrier is maintained to control ‘tight junction’ function.
It has long been known that the brain is protected from alterations elsewhere in the body by a highly regulated gateway known as the blood-brain barrier, which allows only selected … Continue Reading Researchers identify how the blood-brain barrier is maintained to control ‘tight junction’ function.
Study identifies ‘significant’ vascular anomalies in the brains of people with Huntington’s disease.
An international study led by researchers from Université Laval has identified significant vascular changes in the brains of people with Huntington’s disease. This breakthrough, the details of which are published … Continue Reading Study identifies ‘significant’ vascular anomalies in the brains of people with Huntington’s disease.
Do blood vessels that feed tumours differ from other blood vessels? Fourteen years ago, experiments designed to answer that question led to the discovery of several genes that are more … Continue Reading Blood vessel growth in the brain relies on a protein found in tumour blood vessels.
A new study from Weizmann Institute researchers has found evidence of a unique signature that may be the missing link between cognitive decline and aging. The scientists believe that this … Continue Reading Scientists identify the signature of aging in the brain via the blood-brain-barrier.
A new technique developed by Columbia University has demonstrated for the first time that the size of molecules penetrating the blood-brain barrier (BBB) can be controlled using acoustic pressure, the … Continue Reading New non-invasive technique controls the size of molecules penetrating the Blood-Brain Barrier.