Containing a mini-ecology of its own, the human gut contains trillions of bacteria, known as the microbiota, a symbiotic entity crucial for digesting food and regulating the immune system. Gut … Continue Reading Gut microbiota that impairs normal skeletal growth identified.
Critically, the growth of children’s bones depends on growth plates situated close to the end of all long bones in the body. These plates are narrow discs of cartilage providing … Continue Reading New mechanism of bone growth uncovered.
Although bones are hard ossified organs, they have a dense network of blood vessels inside them where bone marrow is located. as well as on their outer surface covered by … Continue Reading Discovery of previously unknown blood vessel system in bones.
The gut is colonized by diverse microorganisms forming a microbial community known as the gut microbiota. Research suggests the gut microbiota immunomodulatory effect influences pathologic conditions centered in the gut, … Continue Reading Antibiotic disruption of the gut microbiome dysregulates skeletal health.
The human skeleton is an amalgam of diverse tissue types including bone, cartilage, and fat cells. Each tissue type in the skeleton is generated and maintained by the precise regulation … Continue Reading Researchers identify elusive human skeletal stem cells.
During exercise, muscle function needs to significantly increase; this requires that the uptake and breakdown of the two main nutrients of myofibers, glucose and fatty acids (FAs), markedly rise. The … Continue Reading First ever bone-derived hormone to affect exercise capacity identified.
Multiple myeloma, also known as myeloma, is a type of bone marrow cancer. Multiple myeloma affects the plasma cells, blood cell, inside the bone marrow. Myeloma does not take the form of a … Continue Reading Study is first to link multiple myeloma protein to extramedullary disease.
Unprecedented precision study identifies the four genes responsible for blood stem cell development.
Every day, over 100 billion new mature blood cells are generated in an adult human. This major production places high demands on the blood stem cells which must be capable … Continue Reading Unprecedented precision study identifies the four genes responsible for blood stem cell development.
Psoriasis is a chronic autoimmune disorder that affects 2% of the world population. It is characterised by inflammation and scaling of the skin, accompanied by a greater risk of contracting … Continue Reading Researchers identify a link between psoriasis and bone loss.
Bone metastasis is the only type of metastasis that can be controlled, but not cured, by drugs. Treatment is only given once the metastasis has been identified, which is normally … Continue Reading Researchers identify the precise gene responsible for metastasis of breast cancer to the bone.
While all red and white blood cells derive from stem cells in the bone marrow, the scientific community has been divided as to whether bone marrow cells are also able … Continue Reading Long-term study uncovers previously unknown mechanism of the formation of fat tissue in humans.
Diabetic neuropathy is a condition in which perpetually high blood sugar causes nerve damage, resulting in a myriad of symptoms such as numbness, reduced ability to detect painful stimuli, muscle … Continue Reading Stem cell injections improve diabetic neuropathy in animal models.
A novel blood test could greatly improve triage of victims of radiation accidents by rapidly predicting who will survive, who will die, and who should receive immediate medical countermeasures, according … Continue Reading New RNA-based blood test quickly reveals severity of radiation injury.
Pre-eclampsia is a disease that affects 5 to 8 percent of pregnancies in America. Complications from this disease can lead to emergency cesarean sections early in pregnancies to save the … Continue Reading Researchers discover previously unknown transitional stem cell.
Telomeres are short stretches of repeated nucleotides that protect the ends of chromosomes. In somatic cells, these protective sequences become shorter with each cellular replication until a critical length is … Continue Reading Large scale human study shows longer telomere length leads to higher cancer mortality.
Scientists at the University of California, Berkeley, have identified a new molecular pathway critical to aging, and confirmed that the process can be manipulated to help make old blood like … Continue Reading Researchers identify new mitochondrial pathway critical to aging.