It is known that the formation of large numbers of polyps in the colon has a high probability of developing into colon cancer, if left untreated. The large-scale appearance of … Continue Reading Previously unknown gene mutation in hereditary colon cancer identified.
Colorectal cancer is the development of cancer from the colon or rectum, due to the abnormal growth of cells that have the ability to invade or spread to other parts … Continue Reading Genetic cause of 15% of all colorectal cancer diagnoses identified.
It is known that chronic inflammation in the gut increases the risk of colon cancer by as much as 500%. Therefore, the genetic basis and mechanism of cancer proliferation in … Continue Reading Researchers show how gut inflammation initiates colon cancer.
Due in part to improvements in screening, the rates of new colorectal cancer diagnoses have been falling in the United States for people ages 50 and older. However, for people … Continue Reading Study identifies different genetic drivers of colorectal cancer in older and younger patients.
Colon cancer is one of the leading causes of cancer-related deaths worldwide, and researchers are hard at work to understand the disease’s complex molecular underpinnings. Now, a study from researchers … Continue Reading Newly identified gene pair in colon cancer challenges whole paradigm on causation.
It has been shown that patterns of poor nutritional intake may exacerbate the elevated morbidity experienced by cancer survivors. While most cancer patients in the United States are motivated to … Continue Reading Large-scale study investigates the diet quality of cancer survivors.
Colorectal cancer is now understood to be definitely linked to microbial problems in the gut. Research has shown that the disease is linked with less numbers and diversity in the … Continue Reading Researchers use gut bacteria to map genetic mutations in colorectal cancer tumours.
Methylation is a process where a methyl group is added into critical points along human DNA. In cancer, many regions of the DNA are not methylated, leading to untimely gene … Continue Reading Researchers identify an epigenetic mechanism for colon cancer proliferation.
Colon cancer is often detected in its earliest stages thanks in part to screening technologies like colonoscopy. By snaking a camera through a patient’s intestines, doctors can identify polyps and … Continue Reading New nanotech contrast enables blood test for precancerous growth in colon cancer.
Liquid biopsy of colorectal cancer shown to be more accurate than tissue biopsy in large-scale study.
Tumour genotype plays an important role in drug resistance in patients with metastatic colorectal cancer, however, the genotype obtained at diagnosis can vary after different treatment lines. Therefore, DNA analysis … Continue Reading Liquid biopsy of colorectal cancer shown to be more accurate than tissue biopsy in large-scale study.
While the overall rate of colorectal cancer is declining, previous studies show that colorectal cancer specifically among young patients is increasing. Results also show that colorectal cancer in patients younger … Continue Reading Human study shows colorectal cancer genetically different in older and younger patients.
Long non-coding RNAs (lncRNA) are unusual in that they don’t encode proteins like normal RNA. Yet they do play a role in regulating cellular functions and interest cancer researchers. Now, … Continue Reading Researchers identify long non-coding RNA which modulates colorectal cancer metabolism.
Scientists from the Spanish National Cancer Research Center (CNIO) have discovered that the MCRS1 protein, in response to an excess of nutrients, induces an increase in the activity of mTOR … Continue Reading Researchers identify an oncogene regulated by nutrients.
In a group of patients diagnosed with colorectal cancer at 40 or younger, 1.3 percent of the patients carried germline TP53 gene mutations, although none of the patients met the … Continue Reading Researchers begin to map inherited gene mutations in colorectal cancer.
Bacteria that are commonly found in the mouth are often abundant in patients with colon cancer, but the potential role these microbes play in tumour development has not been clear. … Continue Reading Bacteria identified which protects intestinal tumours from immune cells.
In recent years, a standard follow-up to colorectal cancer surgery has been to analyze the tumour tissue for the presence of immune cells. Finding high quantities of cytotoxic T cells, … Continue Reading Activated immune cells indicate a favourable prognosis in colorectal cancer.