Living organisms experience various stresses during their lifespans. These stresses include radiation, ultraviolet rays, and chemical substances which directly damage DNA and cause cancer. Organisms are able to speedily repair … Continue Reading Study identifies genes which control cellular senescence.
Tails in lizards and arms in starfish show an astounding ability to regrow, however, mammals have partially lost the capacity to extensively regenerate body parts. The liver is unique among … Continue Reading Researchers use epigenetic mechanism to regenerate mammalian liver.
Due to the recent episodes of severe air pollution in eastern Asia, there is growing concern about the systemic effects of air pollution on human health. Along with the other … Continue Reading Researchers identify mechanism for air pollution-induced liver disease.
In human cells, shortened telomeres, the protective caps at the ends of chromosomes, are both a sign of aging and contribute to it. The effects of chronic diseases such as … Continue Reading Researchers use dietary supplement in atherosclerotic mice to lengthen telomeres.
In the treatment of pain, a common course is to treat patients with opioid medications, these medications show limited effectiveness for neuropathic pain and come with safety and addiction issues. … Continue Reading Researchers map how antidepressants lessen neuropathic pain.
After a hit to the head or rapid whiplash, whether from a car crash, athletic event or other accident, millions of Americans develop traumatic brain injuries (TBIs) each year. TBIs … Continue Reading Large-scale human study shows blood test predicts prognosis for traumatic brain injuries.
Free radicals are especially reactive atoms or groups of atoms that have one or more unpaired electrons. They are produced in the body as a by-product of normal metabolism and … Continue Reading New findings on the free radical theory of aging and mitochondrial damage.
The use of medical imaging for heart disease has exploded in the past decade. These tests expose patients to a nontrivial amount of low-dose radiation. However, nobody really knows exactly … Continue Reading New technology identifies DNA damage in patients undergoing CT scanning.
Idiopathic pulmonary fibrosis (IPF) causes a gradual loss of respiratory capacity and can be lethal within a few years. The cause is unknown, although it can be attributed to a … Continue Reading Researchers identify the causal link between telomere shortening and idiopathic pulmonary fibrosis.
Diabetic neuropathy is a condition in which perpetually high blood sugar causes nerve damage, resulting in a myriad of symptoms such as numbness, reduced ability to detect painful stimuli, muscle … Continue Reading Stem cell injections improve diabetic neuropathy in animal models.
When cells are normal and unstressed, the molecule keeps transcription moving so that genes are ‘expressed’ and RNA is jotted down more quickly. When cells are stressed and transcription runs … Continue Reading Researchers identify key molecule which halts transcription of cell’s genetic code.
Human DNA accumulates damage over time, and older people’s bodies can’t repair it as well. Many scientists believe a build up of damage can cause cells to enter an irreversible … Continue Reading Study identifies molecular link between DNA damage and premature aging.
Inflammatory processes occur in the brain in conjunction with stroke and neurological diseases such as Alzheimer’s and Parkinson’s disease. Researchers from Lund University, the Karolinska Institutet and the University of … Continue Reading New findings on microglial activation during neuroinflammation.
A protein that helps embryonic stem cells retain their identity also promotes DNA repair, according to a study in The Journal of Cell Biology. The findings raise the possibility that … Continue Reading Researchers identify protein responsible for DNA repair at a stem cell level.
Researchers identify gene mutation that raises risk of nerve damage in leukemia patients using Vincristine.
Researchers from St. Jude Children’s Research Hospital have identified the first genetic variation that is associated with increased risk and severity of peripheral neuropathy following treatment with a widely used … Continue Reading Researchers identify gene mutation that raises risk of nerve damage in leukemia patients using Vincristine.
Researchers have discovered a mechanism linked to the brain damage often suffered by stroke victims, and are now searching for drugs to block it. Strokes happen when the blood supply … Continue Reading Researchers identify the mechanism of stroke damage.