A person’s memory is where the brain encodes, stores, and retrieves information, where it can also be used as a record of experience for guiding learned behavior. Different areas of … Continue Reading Specific neurons responsible for location-based memories decoded and identified.
Alzheimer’s disease (AD) is the most common dementia type, with no treatment to slow down the progression of this dehumanizing disease currently available. The mechanisms of AD are poorly understood … Continue Reading Astrocytes linked to Alzheimer’s disease for the first time.
Alzheimer’s disease (AD) is a fatal neurodegenerative disorder as well as the leading cause of senile dementia worldwide, with no effective treatment and limited functionality for early diagnosis. Now, a … Continue Reading Noninvasive eye scan can detect key signs of Alzheimer’s Disease in humans.
Hypertension is a leading risk factor for dementia, however, the mechanisms underlying its damaging effects on the brain are poorly understood. Now, a study from researchers at Weill Cornell Medicine … Continue Reading Immune cells identified as the culprit linking hypertension and dementia.
Study shows that structure of toxic tau aggregates determines type of dementia, and rate of progression.
Recent efforts to develop a treatment for Alzheimer’s disease and other dementias have focused heavily on removing toxic tau proteins from the brain. The tau protein is known to bind … Continue Reading Study shows that structure of toxic tau aggregates determines type of dementia, and rate of progression.
Alzheimer’s disease is characterized by the degeneration of neurons in the hippocampus and cortex, and the appearance of neuritic plaques and neurofibrillary tangles. Although the precise cause of Alzheimer’s disease remains … Continue Reading Researchers elevate brain protein to allay symptoms of Alzheimer’s in animal model.
For decades, scientists have known that people with two copies of a gene called apolipoprotein E4, or ApoE4, are much more likely to have Alzheimer’s disease at age 65 than … Continue Reading Study shows why people with the ApoE4 gene are more susceptible to Alzheimer’s disease.
The CDC estimates that more than 1.3 million Americans visit an emergency department each year because of a TBI-related injury. The late effects of TBI are of great interest, however, … Continue Reading Largest ever study identifies link between TBI and Parkinson’s, but not Alzheimer’s.
It is known that one of the earliest sites of Alzheimer’s disease pathology is the hippocampus, a brain structure critical for the learning and memory processes that falter early in Alzheimer’s … Continue Reading Study shows how Alzheimer’s risk gene disrupts memory replay.
The hippocampus is a critical structure for encoding of novel experiences. A particularly compelling puzzle is how the hippocampus encodes new information in the presence of interference from past memories. … Continue Reading Neuroimaging shows how the brain switches from past to present memory mode.
It is known that during disease, tau protein gets modified, changes its location in nerve cells and then aggregates. In healthy nerve cells, tau resides in a part of the … Continue Reading Previously unknown tau pathway leading to Alzheimer’s disease identified.
In Alzheimer’s, a build-up of plaque and dysfunctional proteins in the brain are known to be hallmarks of the disease. While the majority of Alzheimer’s research has focused on accumulation … Continue Reading New technique reveals that tau predicts Alzheimer’s disease progression.
Brain map researchers release first of it’s kind data on the aging human brain and traumatic brain injury.
Dementia is a common illness with an incidence that is rising as the aged population increases. A multitude of neurodegenerative illnesses have an associated dementia, including corticobasal degeneration, Creutzfeldt–Jakob disease, … Continue Reading Brain map researchers release first of it’s kind data on the aging human brain and traumatic brain injury.
Dendritic spines are specialized protrusions responsible for receiving excitatory synaptic inputs, providing an important function in communication between neurons. The majority of excitatory synapses in the brain exist on dendritic … Continue Reading Novel molecule promotes the neuronal structures associated with memory to grow.
Primary progressive aphasia (PPA) is a form of dementia characterized by degeneration of the language network. In the early stages, PPA is associated with a left-lateralized pattern of cortical atrophy … Continue Reading Neuroimaging can identify start and location of amyloid plaques in living brain.
The incidence of HIV-associated dementia has declined dramatically since the introduction of potent combined antiretroviral therapy; however, milder forms of HIV-associated neurocognitive disorders (HAND) persist. Some 30 to 50 % of … Continue Reading Study shows how neural networks adapt to the presence of a toxic HIV protein.