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Blocking brain signals detected in the kidney could help unlock treatments for kidney failure.

a study from researchers at the University of Bristol discovers an important cell signaling pathway in the kidney holding great potential to treat CKD. The team states they have linked a signaling molecule present in high levels in the brain called Neuropeptide Y (Npy) to raised levels of albuminuria and damage to the glomerulus.

Chronic kidney disease (CKD) is a major public health issue, affecting over 10 percent of the global population, frequently occurring as a result of other disorders such as hypertension, diabetes, obesity, or metabolic syndrome. An early sign of CKD is the increased level of liver protein albumin in the urine, also known as albuminuria. Shown to damage the glomerulus, the

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