The growing worldwide epidemic of respiratory diseases can be attributed to simple everyday factors such as tobacco smoke, air pollution, occupational chemicals, or dust. These diseases involve the infection or … Continue Reading How airway cells work together in regeneration and aging.
Cholera is a contagion that causes chronic diarrhea brought on through the intake of food or water contaminated with the Vibrio cholerae bacterium. Cholera affects roughly 4 million people per … Continue Reading Gut microbiota regulates resistance to cholera.
Chronic kidney disease (CKD) is a major public health issue, affecting over 10 percent of the global population, frequently occurring as a result of other disorders such as hypertension, diabetes, … Continue Reading Blocking brain signals detected in the kidney could help unlock treatments for kidney failure.
Atherosclerosis is a chronic disease involving the build-up of plaque consisting of fat, cholesterol, calcium, and other blood-based substances. Sequentially, the plaque hardens and narrows the arteries to limit the … Continue Reading Molecules alter the gut microbiota to reverse narrowing of arteries in an animal study.
Malaria is a tropical disease affecting humans and animals through the bite of a mosquito, causing fatalities when it is not diagnosed and treated promptly. The majority of malaria cases … Continue Reading Microbe shows promise in controlling the spread of malaria.
Policing what goes in and out of the body, the immune system is a line of defense guarding against infection whilst distinguishing foreign bodies from the person’s healthy tissue. One … Continue Reading Previously unknown human immune cell discovered.
A once primordial parasite, mitochondria are now crucial organelles in cells responsible for producing more than 90% of the energy needed by the body to sustain life and support organ … Continue Reading Proof-of-concept for synthetic enzyme to treat all mitochondrial disorders.
In the vast microscopic world contained within the human body, a universal component of all cell membranes is known as a lipid bilayer, a biological membrane consisting of two layers … Continue Reading Synthetic DNA nanopore selects and transports macromolecules across cell membranes.
A person’s memory is where the brain encodes, stores, and retrieves information, where it can also be used as a record of experience for guiding learned behavior. Different areas of … Continue Reading Specific neurons responsible for location-based memories decoded and identified.
A worldwide rise in immune and inflammatory diseases such as multiple sclerosis and inflammatory bowel diseases has been linked to Western society-based changes in lifestyle and environment. These include decreased … Continue Reading Sunlight affects the gut microbiota and vitamin D levels.
Nearly 12 million adults in the United States have been diagnosed with chronic obstructive pulmonary disease, with roughly 180,000 patients dying annually with end-stage refractory lung diseases. The only option … Continue Reading Donor stem cells used to grow fully functioning lungs in live mice.
Infectious diseases continue to affect and kill a multitude of people worldwide, with vaccination seen as the most powerful weapon against this threat. Vaccines are prepared from weakened forms of … Continue Reading Synthetic vaccine can be stored at warmer temperatures.
There are a staggering estimated 785,000 new heart attack cases in the United States each year, with no gold standard treatment for repairing the resulting damage to cardiac tissue. There … Continue Reading First-in-human trial shows hydrogel to repair heart is safe to inject.
Highly painful in nature, inflammatory bowel diseases (IBD) consisting of Crohn’s and ulcerative colitis are caused by dysregulation of the immune system leading to intestinal inflammation and microbial changes. Numerous … Continue Reading Metabolite produced by gut microbiota from pomegranates reduces inflammatory bowel disease.
Saturated fat in red meat has long been linked to a raised risk of heart disease, with TMAO (trimethylamine N-oxide), a gut microbiota-generated metabolite, also linked to the pathogenesis of … Continue Reading Chronic red meat consumption alters gut microbiota, raises heart disease risk.
A decades-long raging epidemic, obesity has been shown to increase the risk of non-alcoholic fatty liver disease (NAFLD)in at least 30% of obese children, leading to liver failure requiring a … Continue Reading Alterations in infant microbiota linked to childhood obesity and liver disease.