Diffuse gliomas represent 80% of all malignant brain tumours. Adult diffuse gliomas are classified and graded according to histological criteria. However, although histopathology classification is well established it suffers from unstandardized, … Continue Reading Large-scale study identifies new epigenetic subtypes of brain cancer.
Human geneticists have discovered that a region of the genome associated with autism contains genetic variation that evolved in the last 250,000 years, after the divergence of humans from ancient … Continue Reading Geneticists ‘date’ genetic variation associated with autism.
Scientists at the Institut de Recherches Cliniques de Montréal (IRCM) discovered a mechanism that promotes the progression of medulloblastoma, the most common brain tumour found in children. The team found … Continue Reading New discovery could prevent the development of brain tumours in children.
In the largest collaborative study so far, an international team of researchers from the European EuroEPINOMICS consortium, including scientists from VIB and Antwerp University identified novel causes for severe childhood … Continue Reading New genes identified with key role in the development of severe childhood epilepsies.
Dartmouth researchers have found that the genetic mutation BRAFV600E , frequently found in metastatic melanoma, not only secretes a protein that promotes the growth of melanoma tumour cells, but can … Continue Reading Dartmouth research links genetic mutation and melanoma progression.
Researchers from the Lunenfeld-Tanenbaum Research Institute have revealed an exciting and unusual biochemical connection. Their discovery has implications for diseases linked to mitochondria, which are the primary sources of energy … Continue Reading Researchers make scientific history with new cellular connection.
Scientists at The University of Texas have identified genetic mutations in endometrioid endometrial carcinoma (EEC), the most common form of this cancer of the uterine lining. The mutations revealed a … Continue Reading A new form of endometrial cancer has been identified.
Scientists studying depression in teens have discovered that subtle changes in a gene can predict how the brain reacts to stress, which can cause such health issues as depression, post-traumatic … Continue Reading Researchers find multiple new predictors of stress-related illnesses.
Twist, Snail, Slug. They may sound like words in a children’s nursery rhyme, but they are actually the exotic names given to proteins that can generate cells with stem cell-like … Continue Reading Protein ZEB1 promotes breast tumour resistance to radiation therapy.
Physicians at Johns Hopkins have developed blood and saliva tests that help accurately predict recurrences of HPV-linked oral cancers in a substantial number of patients. The tests screen for DNA … Continue Reading Blood and saliva tests predict return of HPV-linked oral cancers.
While developing a new cancer drug, researchers at The Wistar Institute discovered that mice lacking a specific protein live longer lives with fewer age-related illnesses. The mice, which lack the … Continue Reading ‘Rewired’ mice show signs of longer lives with fewer age-related illnesses.
Millions of people in the United States have a circulatory problem of the legs called peripheral vascular disease. It can be painful and may even require surgery in serious cases. … Continue Reading Scientists discover genetic switch that can prevent peripheral vascular disease in mice.
Research conducted at The Scripps Research Institute (TSRI) has discovered links between a set of genes known to promote tumour growth and mucoepidermoid carcinoma, an oral cancer that affects the … Continue Reading Scripps Florida scientists find genetic mutations linked to salivary gland tumours.
Autism spectrum disorder and intellectual disability often occur together and may even share similar genetic causes. Researchers reporting in Cell Reports have now linked mutations in a particular gene to … Continue Reading Mutated gene linked to both autism and intellectual disability.
Children who have been abused or neglected early in life are at risk for developing both emotional and physical health problems. In a new study, scientists have found that maltreatment … Continue Reading Stress tied to change in children’s gene expression related to emotion regulation, physical health.