Researchers at the University of Toronto have uncovered new insights on the genetic causes of Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s disease. These findings could uncover a … Continue Reading Human generational study pinpoints epigenetic cause of Amyotrophic Lateral Sclerosis (ALS).
Fragile X syndrome, an inherited cause of autism and intellectual disability, can have consequences even for carriers of the disorder who don’t have full-blown symptoms. Some carriers may experience social … Continue Reading New previously unseen cellular mechanism identified in Fragile X syndrome.
The first-ever systematic study of the genomes of patients with ALK-negative anaplastic large cell lymphoma (ALCL), a particularly aggressive form of non-Hodgkin’s lymphoma, shows that many cases of the disease … Continue Reading Researchers demystify rare, deadly lymphoma.
Researchers show for the first time that mitochondria are altered in human model of Parkinson’s disease.
It has long been suspected that the most common mutation linked to both sporadic and familial Parkinson’s disease wreaks its havoc by altering the function of mitochondria in neurons that … Continue Reading Researchers show for the first time that mitochondria are altered in human model of Parkinson’s disease.
A small number of children who catch the influenza virus fall so ill they end up in the hospital, perhaps needing ventilators to breathe, even while their family and friends … Continue Reading Epigenetic mutation helps explain why, in rare cases, flu can kill.
New work by scientists from the Children’s Hospital of Philadelphia details how subtle changes in mitochondrial function may cause a broad range of common metabolic and degenerative diseases. Mitochondria are … Continue Reading Steadily rising increases in mitochondrial DNA mutations cause abrupt shifts in disease.
Human geneticists have discovered that a region of the genome associated with autism contains genetic variation that evolved in the last 250,000 years, after the divergence of humans from ancient … Continue Reading Geneticists ‘date’ genetic variation associated with autism.
Scientists at the Institut de Recherches Cliniques de Montréal (IRCM) discovered a mechanism that promotes the progression of medulloblastoma, the most common brain tumour found in children. The team found … Continue Reading New discovery could prevent the development of brain tumours in children.
In the largest collaborative study so far, an international team of researchers from the European EuroEPINOMICS consortium, including scientists from VIB and Antwerp University identified novel causes for severe childhood … Continue Reading New genes identified with key role in the development of severe childhood epilepsies.
A small freshwater fish found in many tropical aquariums may hold the key to unlocking one of the leading causes of respiratory diseases in humans. Scientists from A*STAR’s Institute of … Continue Reading A*STAR scientists link zebrafish genes to human respiratory diseases.
A new 4,000 person study from the Washington University School of Medicine shows that schizophrenia isn’t a single disease but a group of eight genetically distinct disorders, each with its … Continue Reading Schizophrenia not a single disease but multiple genetically distinct disorders.
Dartmouth researchers have found that the genetic mutation BRAFV600E , frequently found in metastatic melanoma, not only secretes a protein that promotes the growth of melanoma tumour cells, but can … Continue Reading Dartmouth research links genetic mutation and melanoma progression.
Researchers from the Lunenfeld-Tanenbaum Research Institute have revealed an exciting and unusual biochemical connection. Their discovery has implications for diseases linked to mitochondria, which are the primary sources of energy … Continue Reading Researchers make scientific history with new cellular connection.
Scientists at The University of Texas have identified genetic mutations in endometrioid endometrial carcinoma (EEC), the most common form of this cancer of the uterine lining. The mutations revealed a … Continue Reading A new form of endometrial cancer has been identified.
Howard Hughes Medical Institute (HHMI) scientists have developed a strategy for finding disease-causing mutations that lurk in only a small fraction of the body’s cells. Such mutations can cause significant … Continue Reading New gene technique identifies hidden causes of brain malformation.
The U.S. Food and Drug Administration has approved Cologuard, the first stool-based colorectal screening test that detects the presence of red blood cells and DNA mutations that may indicate the … Continue Reading FDA approves world’s first non-invasive DNA screening test for colorectal cancer.