Nanomachines made from synthetic DNA motors have the potential to mimic natural protein motors in cells, however, the operation of synthetic DNA motors in living corpuscles has not yet been … Continue Reading Autonomous nanomachines perform biologic functions in live cells.
Living organisms experience various stresses during their lifespans. These stresses include radiation, ultraviolet rays, and chemical substances which directly damage DNA and cause cancer. Organisms are able to speedily repair … Continue Reading Study identifies genes which control cellular senescence.
Cardiovascular diseases are the leading causes of death worldwide and represent a substantial economic burden on public health care systems. Now, a study from researchers at Uppsala University shows that … Continue Reading Large-scale study shows that memory, epigenetics of a heart attack are stored in person’s genes.
According to the World Health Organization, cancer is the leading cause of death worldwide and is projected to increase 45% between 2007 and 2030, which will involve more than 15 … Continue Reading The first epigenetic test to diagnose tumours of unknown origin.
Epigenetic dysfunction is implicated in many neurological and psychiatric diseases, including Alzheimer’s disease and schizophrenia. Consequently, histone deacetylases (HDACs) are being aggressively pursued as therapeutic targets. However, a fundamental knowledge … Continue Reading Researchers image the epigenetics of the human brain for the first time ever.
For decades, textbooks have stated that macromolecules within living cells, such as DNA, RNA, and proteins, do not fluoresce on their own. Technology instead relies on special fluorescence dyes to … Continue Reading Textbooks upended as researchers show that DNA naturally fluoresces.
One of the processes associated with aging is progressive shortening of telomeres, DNA-protecting structures at the ends of chromosomes, like the plastic tips on shoelaces. Each time a cell divides, … Continue Reading Male hormone reverses cell aging, increases telomere length, in clinical trial.
Leukemia, or blood cancer, involves pathological alterations in the body’s hematopoietic system. In acute myeloid leukemia, it is specifically the bone marrow that is affected. In a healthy body, different … Continue Reading Previously unknown cell-death pathway mapped in leukemia cells.
Charcot-Marie-Tooth Disease (CMT) is a family of inherited disorders of the peripheral nervous system, affecting approximately one in 2,500 Americans. Its most common iteration, CMT1, comes in many forms, most … Continue Reading Researchers identify previously unknown genetic cause of inherited neuropathy.
Epigenetics is a research field where DNA methylation or histone acetylation, as opposed to the DNA sequence, are studied as a tool for conveying traits to the next generation. Previously, … Continue Reading New type of epigenetic mark identified in the human cell nucleus.
Approximately 16% of adults in the United States report drug use, however, not everyone who experiments with drugs becomes an addict. Environmental and societal factors play a role in addiction … Continue Reading First ever study identifies epigenetic markers that influence addiction in animal model.
A strand of DNA is a very long, narrow string, just a few nanometers across. Single-molecule orientation measurements provide unparalleled insight into a multitude of biological and polymeric systems. Single-molecule … Continue Reading New imaging technique reveals unprecedented nanoscale details about DNA.
Red blood cells are the most abundant cells in the human body, and transport oxygen and carbon dioxide. Millions of people worldwide suffer from anaemia, a condition in which the … Continue Reading Study identifies the genetic code of red blood cells.
A person’s genetic makeup plays a role in autoimmune diseases such as multiple sclerosis that develop when the body is attacked by its own immune system. However, little is known … Continue Reading Study maps gene variants to DNA regions that regulate immune cells.
Multiple sclerosis (MS) is a neurodegenerative disease in which the immune system attacks the myelin that protects nerve fibers, upsetting the flow of information between the brain and the body. … Continue Reading Human study identifies the genetic cause of familial multiple sclerosis.
Intracellular organelles mediate complex cell-based functions that often require ion-transport across their membranes. Melanosomes are organelles responsible for the synthesis of the major mammalian pigment melanin. Defects in melanin synthesis … Continue Reading Study identifies the protein that puts the brakes on melanin production.