A new study led by investigators at Brigham and Women’s Hospital (BWH) reports the discovery of a genetic variant that is associated with a patient’s likelihood of responding to interferon-beta, … Continue Reading New gene identified in multiple sclerosis disease activity.
Researchers at the University of North Carolina have used exosomes, tiny bubbles of protein and fat produced naturally by cells, to bypass the body’s defenses and deliver a potent antioxidant … Continue Reading Researchers utilize natural exosomes to deliver Parkinson’s treatment directly to brain.
Revolutionary micronpump is 20 times thinner than a hair, delivers drugs to exact location in the brain.
Many potentially efficient drugs have been created to treat neurological disorders, but they cannot be used in practice. Typically, for a condition such as epilepsy, it is essential to act … Continue Reading Revolutionary micronpump is 20 times thinner than a hair, delivers drugs to exact location in the brain.
Depression affects an estimated 350 million people worldwide and poses a major public health challenge, according to the World Health Organization. Researchers have discovered an unconventional way that serotonin is … Continue Reading New source of serotonin in the brain found and the effects on SSRI’s identified.
A team of investigators at Children’s Hospital Los Angeles and the University of Southern California have developed the first fully implantable micropacemaker designed for use in a fetus with complete … Continue Reading Researchers develop the first fully-implantable micropacemaker designed for fetal use.
Columbia University Medical Center (CUMC) researchers have pinpointed the immune system mechanism that allows a kidney transplant to be accepted without lifelong immunosuppressive drugs, a significant step toward reducing or … Continue Reading Kidney transplant tolerance mechanism identified.
Researchers identify gene mutation that raises risk of nerve damage in leukemia patients using Vincristine.
Researchers from St. Jude Children’s Research Hospital have identified the first genetic variation that is associated with increased risk and severity of peripheral neuropathy following treatment with a widely used … Continue Reading Researchers identify gene mutation that raises risk of nerve damage in leukemia patients using Vincristine.
Nanometer-sized drones that deliver a special type of healing molecule to fat deposits in arteries could become a new way to prevent heart attacks caused by atherosclerosis, if an animal … Continue Reading Nanobot ‘drones’ successfully target atherosclerosis in animal model.
Cholera is caused when the bacterium Vibrio cholerae infects the small intestine. The disease is characterized by acute watery diarrhea resulting in severe dehydration. EPFL scientists have now demonstrated that … Continue Reading Scientists identify Cholera’s mode of horizontal gene transfer and drug-resistance.
A team of researchers led by Duke Cancer Institute have identified key events that prompt certain cancer cells to develop resistance to otherwise lethal therapies. By mapping the points of … Continue Reading Researchers begin to map epigenetic methylation in specific cancer drug resistance.
The U.S. Food and Drug Administration (FDA) has cleared the EnLite Neonatal TREC Kit for the company PerkinElmer, the first screening test permitted to be marketed by FDA for Severe … Continue Reading The FDA clears the first-ever newborn test to detect Severe Combined Immunodeficiency.
Within a few months after drug withdrawal, patients in recovery from dependence on prescription pain medications may show signs that the body’s natural reward systems are normalizing. The study from … Continue Reading Researchers map clinical neuroimaging markers for opioid withdrawal.
Researchers from Boston Children’s Hospital and Massachusetts Institute of Technology have developed a targeted drug-delivery system that’s based on a combination of ultraviolet (UV) light and short, single strands of DNA … Continue Reading Researchers use DNA paired with light to deliver drugs on target.
An important development in understanding how the bacterium that causes pneumonia, meningitis and septicemia remains harmlessly in the nose and throat has been discovered by scientists. Streptococcus pneumoniae is a ‘commensal’, which can live harmlessly in the nasopharynx as part of the body’s natural bacterial flora. However, in the very young and old it can invade the rest of the body, leading to serious diseases such as pneumonia, sepsis and meningitis, which claim up to a million lives every year worldwide.
Thoughts health innovators?
“When you discover something novel the medical imperative is to come up with a good use for it” ….. Paul Janssen I was approached to report on a Reuters webinar … Continue Reading Healthinnovations on Thomson Reuters: New Techniques in Drug Discovery.
We know that obesity kills, we know that obesity costs the global economy billions, what we don’t know is how to sustainably treat obesity to bring the former points to … Continue Reading Healthinnovations on the BBC World panel on the Danish ‘Fat Tax’ [unedited]