The human heart has four valves, thin membranes known to open and close to control blood flow through the heart and the rest of the body. When the valves do … Continue Reading New type of immune cell discovered is crucial for heart valve formation.
Researchers use AI to rescue embryos from brain defects by re-engineering cellular voltage patterns.
Improper neural patterning during brain development leads to serious disorders such as open neural tube defects, brain malformations, and susceptibility to autism or degenerative disorders. There are currently no clinically … Continue Reading Researchers use AI to rescue embryos from brain defects by re-engineering cellular voltage patterns.
The basic human body plan, the arrangement of organs in the body, is laid down during embryonic development. Insight into the formation of this plan informs researchers re normal development … Continue Reading New 3D atlas of human embryonic growth clears up many misconceptions on development.
Research into bioengineering has led to important achievements in recent years, with a number of different tissue types being developed. In the area of skin tissue epithelial cells have been … Continue Reading Researcher successfully grow complex, implantable, skin tissue for the first time.
It has long been known that transcriptional regulation during embryonic development relies on the regulation of thousands of genes. Within a particular cell type defined sets of DNA-binding transcription factors … Continue Reading Researchers map how transcription factors interact to create a heart.
More than 40,000 babies in the United States, or about 1 in 100 births, are born annually with a congenital heart defect. Congenital heart defect, is a problem in the … Continue Reading Researchers identify natural triggers to ‘override’ congenital heart defect in newborns.
The heart is arguably the hardest working muscle in the human body and without its incessant, regular beating the body’s organs would be starved of life-giving nutrients. Yet how the … Continue Reading Researchers identify precision medicine for the development of healthy heart muscle.
Heart regeneration a step closer as researchers identify progenitor cell exclusively for heart muscle.
Future therapies for failing hearts are likely to include stem-like cells and associated growth factors that regenerate heart muscle. Now, researchers from the University of Pennsylvania have just taken an … Continue Reading Heart regeneration a step closer as researchers identify progenitor cell exclusively for heart muscle.
Mitochondrial diseases are maternally inherited genetic disorders that cause a wide spectrum of debilitating conditions and which currently have no cure. In a new opensource study published in the journal … Continue Reading Researchers successfully ‘edit’ mitochondrial DNA to prevent inherited disease in animal model.
Researchers at the University of Michigan and UC Davis have solved a genetic mystery that has afflicted three unrelated families, and possibly others, for generations. These families have been plagued … Continue Reading Researchers map rare mutation causing vitamin A deficiency and eye deformities.
The kidney carries out vital functions by continuously filtering the blood and excreting waste products into the urine. This is achieved by a complex system of tubules which transports the … Continue Reading Researchers discover previously unseen regulatory network in the kidney.
During pregnancy, the mother supplies the fetus with nutrients and oxygen via the placenta. If placental development is impaired, this may lead to growth disorders of the embryo or to … Continue Reading Researchers discover a new signaling pathway in embryonic development.
Researchers from the NYU Langone Medical Center and New York University have demonstrated that a specialized DNA-binding protein called CTCF is essential for the precise expression of genes that control … Continue Reading Researchers identify specialized protein crucial for normal neurodevelopment.
The signal molecule, retinoic acid, is a product of vitamin A which helps to instruct how different types of tissue are to be formed in the growing embryo. For the … Continue Reading Previously unknown effect of vitamin A on embryonic development identified.
A Mount Sinai-led research team has discovered a new kind of stem cell that can become either a liver cell or a cell that lines liver blood vessels. The existence … Continue Reading Researchers discover new type of stem cell.
Scientists have grown a fully functional organ from transplanted laboratory-created cells in a living animal for the first time. The researchers have created a thymus, an organ next to the … Continue Reading World’s first working organ grown in an animal from lab-created cells.