Mutations in a gene that helps repair damaged chromosome ends may make smokers, especially female smokers, more susceptible to emphysema, according to results of a new study led by Johns Hopkins researchers. The mutations are one of a few genetic factors directly linked to chronic obstructive pulmonary disease (COPD), including emphysema, since the 1960s. Specifically, the alteration occurs in the telomerase reverse transcriptase (TERT) gene, … Continue reading Epigenetic mutation which shortens telomeres linked to greater emphysema risk in smokers.