Cardiovascular diseases are the leading causes of death worldwide and represent a substantial economic burden on public health care systems. Now, a study from researchers at Uppsala University shows that … Continue Reading Large-scale study shows that memory, epigenetics of a heart attack are stored in person’s genes.
The children of traumatized people have long been known to be at increased risk for post-traumatic stress disorder (PTSD). However, there are very few opportunities to examine biologic alterations in … Continue Reading Trauma’s inherited epigenetic fingerprint observed in children of Holocaust survivors.
According to the World Health Organization, cancer is the leading cause of death worldwide and is projected to increase 45% between 2007 and 2030, which will involve more than 15 … Continue Reading The first epigenetic test to diagnose tumours of unknown origin.
Epigenetic dysfunction is implicated in many neurological and psychiatric diseases, including Alzheimer’s disease and schizophrenia. Consequently, histone deacetylases (HDACs) are being aggressively pursued as therapeutic targets. However, a fundamental knowledge … Continue Reading Researchers image the epigenetics of the human brain for the first time ever.
Epigenetics is a research field where DNA methylation or histone acetylation, as opposed to the DNA sequence, are studied as a tool for conveying traits to the next generation. Previously, … Continue Reading New type of epigenetic mark identified in the human cell nucleus.
Approximately 16% of adults in the United States report drug use, however, not everyone who experiments with drugs becomes an addict. Environmental and societal factors play a role in addiction … Continue Reading First ever study identifies epigenetic markers that influence addiction in animal model.
Obesity has become a major health threat, affecting more than half a billion people worldwide in 2014. In particular, obesity increases the risk for insulin resistance, hypertension, coronary heart disease … Continue Reading Epigenetic modification which raises obesity risk and predicts fatty liver identified.
Tails in lizards and arms in starfish show an astounding ability to regrow, however, mammals have partially lost the capacity to extensively regenerate body parts. The liver is unique among … Continue Reading Researchers use epigenetic mechanism to regenerate mammalian liver.
Preterm birth is a leading cause of infant mortality that can lead to poor life-long health and adverse neurodevelopmental outcomes. The physiologic mechanisms that precede preterm labor remain elusive, and … Continue Reading Epigenetics and environmental factors identified in preterm birth.
The body has an army of millions of immune cells. These cells contain receptors generated through random genetic rearrangements, a clever strategy to keep them ready to fight unfamiliar viruses … Continue Reading Previously unknown immune cell identified, with implications for T1 diabetes.
In a cancerous breast, researchers have seen the problems with the various components of breast tissue and could not fully explain why they happened. The tissue, called the stroma, includes … Continue Reading Human study identifies new gene as cause and early indicator of breast cancer.
It is known that glucose is an essential fuel for brain energy metabolism as well as oxygen. Functional activation of neurons is normally associated with increases in the local cerebral … Continue Reading Neuroimaging shows genetics and environment affect different regions of brain.
Mitochondria are the cellular powerplant and, reliant on nutrient status, it is known that Vitamin B turns mitochondria into cellular builders. Through vitamin B, mitochondria produce substances to make ingredients … Continue Reading Mitochondria dysfunction shown to cause vitamin b imbalance and genetic changes.
Diffuse gliomas represent 80% of all malignant brain tumours. Adult diffuse gliomas are classified and graded according to histological criteria. However, although histopathology classification is well established it suffers from unstandardized, … Continue Reading Large-scale study identifies new epigenetic subtypes of brain cancer.
It is known that the regenerative capacity of the injured central nervous system (CNS) in adult mammals is severely limited, yet axons in the peripheral nervous system (PNS) regrow, albeit … Continue Reading Gene pathway responsible for peripheral nervous system regeneration identified.
As the population continues to age, the need for biological measures of age and more precise screening tests for age-related diseases is becoming increasingly urgent. Epigenetics serves as an intersection … Continue Reading New epigenetic predictor of cancer validated in human study.