Type 2 diabetes is a chronic illness characterised by the presence of elevated blood glucose levels. It accounts for between 80 and 90% of diabetes cases and is one of … Continue Reading Large-scale study identifies an epigenetic marker for Type 2 diabetes.
Current estimates place obesity incidence at more than 600 million individuals worldwide. As a prime risk factor for heart disease, stroke, cancer, type 2 diabetes, and neurodegeneration, obesity poses a … Continue Reading Researchers identify an epigenetic switch for obesity.
The human nervous system is made up of an astonishing diversity of neurons. And yet only a very small number of proteins are needed to generate and determine the identity … Continue Reading Researchers identify a previously unknown regulatory mechanism of neurogenesis.
Major depressive disorder is a highly familial illness and the leading cause of disability worldwide for persons 15 to 44 years of age. It is associated with increased mortality resulting … Continue Reading Study shows that both genetics and environment impact depression.
Alzheimer’s disease poses a health problem of pandemic proportions. It is estimated that by the year 2030 there will be greater than 60 million people worldwide with AD, and $375 … Continue Reading Newly identified role for ApoE explains its effects in Alzheimer’s.
The metastatic progression of breast cancer accounts for the majority of disease-related mortality. However, despite the advent of advanced technologies, the discovery of new metastasis suppressor genes that prevent the … Continue Reading Major epigenetic metastasis-supressor identified for breast cancer.
When pathogens infect the cells of the body, the infection sets off a chain reaction involving the immune system that changes the expression of hundreds of genes. Gene expression is … Continue Reading Multiple signatures left on the immune system by viral infections identified for the first time.
Epigenetics is a process whereby environmental factors can affect DNA and the mechanism by which DNA is transcribed and translated into proteins. Epigenetic regulation has been observed to affect a … Continue Reading Researchers reprogram social behaviour in carpenter ants using epigenetic drugs.
In the late diagnosis of autism spectrum disorder (ASD), a risk factor that has been repeatedly identified is a low birth weight or low gestational age at the time of … Continue Reading Neuroimaging identifies markers in premature babies who later develop autism.
A fundamental law of genetics states that progenies do not inherit epigenetically-based adaptive, pathological or neural features acquired in response to environmental conditions. However, recent studies seem to contradict this … Continue Reading Researchers map ‘epigenetic inheritability’ in fathers sperm caused by diet.
How HIV-1 overcomes the person’s defenses and infects their cells has been studied intensively for over 30 years. While much has been learned, there remain events in the viral life … Continue Reading Researchers reveal and image new phase of HIV infection for the first time.
A leading cause of cancer deaths worldwide, colon cancer is famously resistant to treatment. One reason for this is a group of persisting cancer cells in the colon that cause … Continue Reading Researchers use vitamin A to prevent relapsing colon cancer.
Herpes simplex virus (HSV) is found in the brain cells of approximately 90% of the world’s population and leads to cold sores, recurrent eye infections, genital lesions, and in rare … Continue Reading Study shows how the herpes simplex virus reactivates in neurons.
Obesity is a metabolic disorder resulting from behavioral and heritable causes. Children of obese fathers are at higher risk of developing metabolic disease later in life, independent of the body … Continue Reading Study maps epigenetics of father’s weight passed on by his sperm.
Aging is a major risk factor for many human diseases, and in vitro generation of human neurons is an attractive approach for modeling aging-related brain disorders. While aggressive familial early … Continue Reading New technique enables researchers to grow old human brain cells for the first time.
All mammals, including humans, have two types of fat with completely opposite functions. These are white fat, which stores energy and is linked with diabetes and obesity; and brown fat, … Continue Reading Researchers identify epigenetic switch which generates calorie-burning brown fat.