Chronic kidney disease (CKD) is a major public health issue, affecting over 10 percent of the global population, frequently occurring as a result of other disorders such as hypertension, diabetes, … Continue Reading Blocking brain signals detected in the kidney could help unlock treatments for kidney failure.
There are a staggering estimated 785,000 new heart attack cases in the United States each year, with no gold standard treatment for repairing the resulting damage to cardiac tissue. There … Continue Reading First-in-human trial shows hydrogel to repair heart is safe to inject.
Thrombosis occurs when blood clots disrupt the normal flow of blood in the body, which can cause severe health problems such as pulmonary embolism, heart attack or stroke. Current treatments … Continue Reading Smart patch successfully monitors blood to release blood thinners as needed in animal model.
During a heart attack, clots or narrowed arteries block blood flow, harming or killing cells within the tissue. However, the damage doesn’t end after the crushing pain subsides. The heart’s … Continue Reading Injectable gel used to prevent heart failure in animal model after heart attack.
Heart failure is one of the main health problems worldwide, and the urgent medical needs relating to it have positioned cardiovascular research as one of the most actively evolving fields … Continue Reading Study links adult heart regeneration to telomere length in animal model.
Heart muscle is activated by ionized calcium, with the signaling pathway utilising allosteric mechanisms in the thin filament. Knowledge about the structure-function relationship among proteins in this filament is critical … Continue Reading Previously unknown protein critical to heart muscle contraction identified.
The heart is the organ responsible for pumping blood and supplying nutrients and oxygen to all organs and cells of the body. The cells charged with these functions are the … Continue Reading Researchers identify link between a mitochondrial defect and heart disease.
Cerebral blood flow is rigorously regulated by various mechanisms to safeguard the match between cerebral metabolic demand and supply. The question of how a change in heart health affects cerebral … Continue Reading Large-scale human study identifies link between early-stage heart and brain disease.
Caring for patients with heart failure costs the United States $40 billion a year. Despite the condition’s enormous impact, few new treatments have been developed, and those that exist produce … Continue Reading Human study identifies sleep gene linked to heart failure.
Acute liver failure is a rare yet life-threatening disease for young children. It often occurs extremely rapidly, for example, when a child has a fever. Yet in around 50 percent … Continue Reading Researchers identify new gene responsible for liver disease.
A petite 44-year-old woman has become the first patient in the world to be bridged to a successful heart transplant, that is, to go from needing a transplant to receiving … Continue Reading First patient in the world bridged to a successful heart transplant via a Total Artificial Heart.
The human heart makes precious few new cells but manages to generate billions of life-sustaining beats as it grows old. Now research conducted in fruit flies, rats and monkeys by … Continue Reading Researchers identify protein that protects heart function into old age.
In a study of more than 8,000 veterans living in Hawaii and the Pacific Islands, researchers from Ohio State University, University of Minnesota, and The Department of Veterans Affairs found those … Continue Reading First large-scale longitudinal study links PTSD to heart disease.
A team of researchers from the University of Pittsburgh state that it might be possible to heal cirrhotic liver disease by rebooting the genes that control liver cell function. If … Continue Reading Rebooting cell programming via precision medicine reverses liver failure in animal model.
Researchers from the UC San Diego and the University of Iowa have identified a key piece in the complex molecular puzzle underlying heart failure, a serious and sometimes life-threatening disorder affecting more … Continue Reading Researchers identify protein responsible for epigenetic change in heart failure.
Premature ovarian failure, also known as primary ovarian insufficiency (POI), affects 1% of all women worldwide. In most cases, the exact cause of the condition, which is often associated with … Continue Reading Genetic mutation identified as cause of human ovarian failure.