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Study identifies cause of dendritic pruning defect linked to autism and schizophrenia.

Memories are formed at structures in the brain known as dendritic spines which communicate with other brain cells via synapses. It is known that the number of these brain connections … Continue Reading Study identifies cause of dendritic pruning defect linked to autism and schizophrenia.

Researchers use A3 adenosine receptors to activate ‘off signals’ for chronic pain.

In a new study from Saint Louis University, researchers discovered that drugs targeting the A3 adenosine receptor can turn off pain signals in the spinal cord to provide relief from … Continue Reading Researchers use A3 adenosine receptors to activate ‘off signals’ for chronic pain.

Discovery of new drug targets for memory impairment in Alzheimer’s Disease.

Discovery of new drug targets for memory impairment in Alzheimer’s Disease. A study from KIST has revealed the novel mechanism of how Alzheimer’s patients might lose their memory. The researchers also propose new therapeutic targets, which include GABA production and release mechanisms in reactive astrocytes for treatment of Alzheimer’s disease. Furthermore, we provide a stepping stone for the development of MAO-B inhibitors with long lasting efficacy.

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