During neurodevelopment, the brain fabricates an incredible number of neurons which then migrate to specific parts of the brain. The development of new neurons is active all the way through … Continue Reading Study identifies how adult brain circuits regulate new neuron production.
The age-old feeling of hunger, driven by negative energy balance, elicits the craving and consumption of food, and whilst this survival response is in part mediated by neurons in the … Continue Reading Two new networks of neurons identified in appetite regulation.
Memories are formed at structures in the brain known as dendritic spines which communicate with other brain cells via synapses. It is known that the number of these brain connections … Continue Reading Study identifies cause of dendritic pruning defect linked to autism and schizophrenia.
In the mammalian central nervous system, neurons receive inhibitory synaptic inputs from gamma-aminobutyric acid (GABA)ergic interneurons and excitatory inputs from glutamatergic neurons. Evidence suggests that the dysfunction of appropriate GABAergic … Continue Reading Study implicates two genes in the cause of schizophrenia, vital for signalling balance.
Previous studies have shown that the connection in the adult brain are hard to change, while in children, novel experiences rapidly mold new connections during critical periods of brain development. … Continue Reading Researchers reactivate juvenile neural plasticity in adult brains.
A new study by Brown University neuroscientists details how the neocortex selectively samples from the flow of sensory information that might otherwise flood it. The team state that the usual … Continue Reading Researchers begin to map the corticothalamic pathway in selective neuroplasticity.
In a new study from Saint Louis University, researchers discovered that drugs targeting the A3 adenosine receptor can turn off pain signals in the spinal cord to provide relief from … Continue Reading Researchers use A3 adenosine receptors to activate ‘off signals’ for chronic pain.
Researchers at University of California have identified a control mechanism for an area of the brain that processes sensory and emotive information that humans experience as ‘disappointment.’ The discovery of … Continue Reading Scientists discover ‘dimmer switch’ for mood disorders.
Scientists at The Scripps Research Institute (TSRI) have solved the mystery of why a specific signalling pathway can be associated with alcohol dependence. This signalling pathway is regulated by a … Continue Reading Scientists link alcohol-dependence gene to neurotransmitter.
Discovery of new drug targets for memory impairment in Alzheimer’s Disease. A study from KIST has revealed the novel mechanism of how Alzheimer’s patients might lose their memory. The researchers also propose new therapeutic targets, which include GABA production and release mechanisms in reactive astrocytes for treatment of Alzheimer’s disease. Furthermore, we provide a stepping stone for the development of MAO-B inhibitors with long lasting efficacy.
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