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Researchers identify 2 distinct genetic subtypes in Crohn’s disease patients.

Crohn’s disease, a common inflammatory disorder of the intestinal tract, can have devastating consequences for a patient’s quality of life. Although people with the disease are typically treated with powerful … Continue Reading Researchers identify 2 distinct genetic subtypes in Crohn’s disease patients.

Study identifies immune cells critical for the development of fibrosis in Crohn’s disease.

It is known that patients with Crohn’s disease have uncontrolled inflammation in their gut, which can lead to intestinal fibrosis and narrowing that can slow or block the movement of … Continue Reading Study identifies immune cells critical for the development of fibrosis in Crohn’s disease.

Trauma’s inherited epigenetic fingerprint observed in children of Holocaust survivors.

The children of traumatized people have long been known to be at increased risk for post-traumatic stress disorder (PTSD). However, there are very few opportunities to examine biologic alterations in … Continue Reading Trauma’s inherited epigenetic fingerprint observed in children of Holocaust survivors.

Researchers image the epigenetics of the human brain for the first time ever.

Epigenetic dysfunction is implicated in many neurological and psychiatric diseases, including Alzheimer’s disease and schizophrenia. Consequently, histone deacetylases (HDACs) are being aggressively pursued as therapeutic targets. However, a fundamental knowledge … Continue Reading Researchers image the epigenetics of the human brain for the first time ever.

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