A neuron is an electrically excitable cell that processes and transmits information through electrical and chemical signals in the brain. These signals between neurons occur via synapses, which connect to … Continue Reading Study maps neurogenetics of dendritic growth and formation.
Approximately 16% of adults in the United States report drug use, however, not everyone who experiments with drugs becomes an addict. Environmental and societal factors play a role in addiction … Continue Reading First ever study identifies epigenetic markers that influence addiction in animal model.
Telomere dysfunction has been proposed as a key event that causes cancer progression. According to this model, progressive telomere shortening results in telomere dysfunction and end-to-end chromosomal fusions. The resulting … Continue Reading Researchers identify telomere-based mechanism which turns mutant cells into aggressive cancers.
It is known that one of the earliest sites of Alzheimer’s disease pathology is the hippocampus, a brain structure critical for the learning and memory processes that falter early in Alzheimer’s … Continue Reading Study shows how Alzheimer’s risk gene disrupts memory replay.
Intracellular organelles mediate complex cell-based functions that often require ion-transport across their membranes. Melanosomes are organelles responsible for the synthesis of the major mammalian pigment melanin. Defects in melanin synthesis … Continue Reading Study identifies the protein that puts the brakes on melanin production.
Multiple Sclerosis (MS) is a neurological disease, characterised by demyelination and the onset of chronic, neurodegenerative damage of the central nervous system. Right now, its causes are unknown although various … Continue Reading Researchers identify a new gene involved in Multiple Sclerosis.
People with diabetes have a two to five time higher risk of developing cardiovascular diseases. For decades physicians have noticed unhealthy changes in the hearts of diabetics called diabetic cardiomyopathy, … Continue Reading Study identifies RNA-based mechanism underlying how diabetes damages the heart.
Melanoma is the deadliest skin cancer whose rates have doubled over the last three decades, killing approximately 10,130 people annually. More than 90% of melanoma skin cancers develop because of … Continue Reading Researchers identify ‘sunscreen gene’ that suppresses skin cancer.
Obesity has become a major health threat, affecting more than half a billion people worldwide in 2014. In particular, obesity increases the risk for insulin resistance, hypertension, coronary heart disease … Continue Reading Epigenetic modification which raises obesity risk and predicts fatty liver identified.
The intestines’ primary role is digestion, however, they must also achieve high performance around the clock defending against pathogens and environmental pollutants. This is because everything taken up with food … Continue Reading Study shows how an important intestinal immune response controller works.
The human immunodeficiency virus (HIV) is a lentivirus which causes HIV infection and over time AIDS. Developing effective prevention measures for HIV is hindered by incomplete knowledge of the phenotype … Continue Reading New technology lights up location of first cells to be infected in female HIV transmission.
Now, researchers at Peter MacCallum Cancer Centre have identified a link between the BRCA1 gene mutation and lower levels of a hormone that is an indicator of the number of … Continue Reading Gene mutation implicated in cancer also linked to lower fertility in women.
The earliest events that occur following mucosal HIV-1 exposure remain poorly understood, largely because the eclipse period of infection prior to the detectable disease is very difficult to study in … Continue Reading Earliest ever events following HIV infection mapped for the first time.
It is known that the cells inside a malignant cancer tumour differ a lot. While some cancer cells do not cause trouble, others become aggressive and start to spread, or … Continue Reading Protein which characterises and regulates the spread of aggressive cancer cells identified.
It is known that Parkinson’s disease, the second most common neurodegenerative disease, has genetic causes in 15% of cases. It has been shown that premature aging of dopaminergic neurons in the … Continue Reading Study shows how defective gene prematurely ages neurons in Parkinson’s disease.
The innate immune system is hard-wired to protect people from infection. However, mutations in these protective genes can lead to uncontrolled inflammation, resulting in autoinflammatory disease. Autoinflammatory diseases are characterized … Continue Reading Precision medicine study identifies decades-old mysterious, rare and debilitating disease.