Survival rates for patients with lung cancer increase dramatically the earlier the disease is diagnosed, underscoring the need for effective biomarkers that can be used for detection. Now, scientists at … Continue Reading Researchers discover ‘highly effective’ new biomarker for lung cancer in human trials.
While abnormalities in the adrenergic and noradrenergic systems, both integral in the fight-or-flight response, are thought to play a role in the development of post-traumatic stress disorder (PTSD), until now … Continue Reading Evidence of genetic link to PTSD in soldiers exposed to childhood trauma.
A small freshwater fish found in many tropical aquariums may hold the key to unlocking one of the leading causes of respiratory diseases in humans. Scientists from A*STAR’s Institute of … Continue Reading A*STAR scientists link zebrafish genes to human respiratory diseases.
Scientists at The University of Texas have identified genetic mutations in endometrioid endometrial carcinoma (EEC), the most common form of this cancer of the uterine lining. The mutations revealed a … Continue Reading A new form of endometrial cancer has been identified.
An international team of researchers has identified a new inherited neuromuscular disorder. The rare condition is the result of a genetic mutation that interferes with the communication between nerves and … Continue Reading A new rare neuromuscular disease has been discovered by researchers.
A new study finds a wide range of epigenetic changes, alterations in DNA across the genome that may be related to key environmental exposures, in children with Crohn’s disease (CD), … Continue Reading Study shows epigenetic changes in children with Crohn’s Disease.
Howard Hughes Medical Institute (HHMI) scientists have developed a strategy for finding disease-causing mutations that lurk in only a small fraction of the body’s cells. Such mutations can cause significant … Continue Reading New gene technique identifies hidden causes of brain malformation.
A newborn screening test for severe combined immunodeficiency (SCID) reliably identifies infants with this life-threatening inherited condition, leading to prompt treatment and high survival rates, according to a study supported … Continue Reading Test reliably detects inherited immune deficiency in newborns.
A microfluidic device developed at Massachusetts General Hospital (MGH) may help study key steps in the process by which cancer cells break off from a primary tumour to invade other … Continue Reading Novel device captures moment of tumour metastases.
The U.S. Food and Drug Administration has approved Cologuard, the first stool-based colorectal screening test that detects the presence of red blood cells and DNA mutations that may indicate the … Continue Reading FDA approves world’s first non-invasive DNA screening test for colorectal cancer.
Scientists at A*STAR’s Institute of Medical Biology (IMB) have found new clues to early detection and precision treatment of ovarian cancer, currently one of the most difficult cancers to diagnose … Continue Reading A*STAR scientists make breakthroughs in ovarian cancer research.
Researchers with The Cancer Genome Atlas (TCGA) Research Network have completed the largest, most diverse tumour genetic analysis ever conducted, revealing a new approach to classifying cancers. The work, led … Continue Reading Largest-ever cancer genetic analysis reveals new way of classifying cancer.
Nature is thrifty. The same signals that embryonic cells use to decide whether to become nerves, skin or bone come into play again when adult animals are learning whether to … Continue Reading Notch developmental pathway regulates fear memory formation.
Researchers and doctors at the Institute of Bioengineering and Nanotechnology (IBN), Singapore General Hospital (SGH) and National Cancer Centre Singapore (NCCS) have co-developed the first molecular test kit that can … Continue Reading First ever kidney cancer molecular test predicts patient’s survival and drug response.
Physicians at Johns Hopkins have developed blood and saliva tests that help accurately predict recurrences of HPV-linked oral cancers in a substantial number of patients. The tests screen for DNA … Continue Reading Blood and saliva tests predict return of HPV-linked oral cancers.
While developing a new cancer drug, researchers at The Wistar Institute discovered that mice lacking a specific protein live longer lives with fewer age-related illnesses. The mice, which lack the … Continue Reading ‘Rewired’ mice show signs of longer lives with fewer age-related illnesses.