A once primordial parasite, mitochondria are now crucial organelles in cells responsible for producing more than 90% of the energy needed by the body to sustain life and support organ … Continue Reading Proof-of-concept for synthetic enzyme to treat all mitochondrial disorders.
In the past chimeras, an unnatural amalgamation of two different species was the stuff of futuristic sci-fiction comics, today this promising genetic engineering technique is less scary as it becomes … Continue Reading First pig-monkey chimera engineered and born.
For the greatest chance of survival, cancer screening needs to detect the disease before symptoms appear. Current cancer detection involves blood tests, urine tests, DNA tests, and/or medical imaging, however, … Continue Reading DNA computer can detect cancer on a single-cell basis.
Mining the gut microbiota, the trillions of microbes living in our digestive system is a promising approach for developing new sensors providing a response to disease and abnormalities in the … Continue Reading Bacteria containing DNA computer provides diagnostics for the gut microbiota.
Cellular metabolism is the sum of all chemical changes occurring in living organisms in order to maintain life, including the synthesis of new molecules, and the breakdown and removal of … Continue Reading Researchers induce artificial metabolism in synthetic DNA.
Approximately half the adult population in the United States is suffering from back or neck pain whose treatment and care costs result in an estimated 195 billion USD a year. … Continue Reading Spinal discs made of engineered living tissue implanted in large animal model.
When reproducing some reptiles, amphibians, and fish can procreate with same-sex parents, however, it’s challenging for mammals to do the same even with the help of fertilization technology. Now, a … Continue Reading Researchers produce mouse pups with same-sex parents.
Organ transplants save thousands of lives every year, however, there is an acute shortage of human donors. This shortage has led to attempts to develop animal organs capable of being … Continue Reading Genetic ‘dial’ to control body size in pigs identified.
It is known that Alzheimer’s disease is more common in African-Americans than Caucasians, however, the Alzheimer’s disease genetic risk profile for African-Americans is poorly understood. While more than 20 genes have … Continue Reading Study identifies 2 new genes responsible for Alzheimer’s disease among African-Americans.
Leukemia, or blood cancer, involves pathological alterations in the body’s hematopoietic system. In acute myeloid leukemia, it is specifically the bone marrow that is affected. In a healthy body, different … Continue Reading Previously unknown cell-death pathway mapped in leukemia cells.
Red blood cells are the most abundant cells in the human body, and transport oxygen and carbon dioxide. Millions of people worldwide suffer from anaemia, a condition in which the … Continue Reading Study identifies the genetic code of red blood cells.
A person’s genetic makeup plays a role in autoimmune diseases such as multiple sclerosis that develop when the body is attacked by its own immune system. However, little is known … Continue Reading Study maps gene variants to DNA regions that regulate immune cells.
The innate immune system is hard-wired to protect people from infection. However, mutations in these protective genes can lead to uncontrolled inflammation, resulting in autoinflammatory disease. Autoinflammatory diseases are characterized … Continue Reading Precision medicine study identifies decades-old mysterious, rare and debilitating disease.
It is known that the age-related growth differentiation factor 11 (GDF11) is member of the transforming growth factor β superfamily of proteins. Circulating GDF11 concentrations appear to decline with age, … Continue Reading Study identifies previously unknown molecular pathway in aging.
Malaria is one of the world’s leading health problems. More than 40 percent of the world’s population live in areas where there is a risk of contracting the disease. According … Continue Reading Researchers successfully genetically-engineer mosquitoes which can’t carry malaria.
An enzyme called telomerase plays a significant role in aging and most cancers. Telomerase’s primary job is to maintain the DNA in telomeres, the structures at the ends of a … Continue Reading Study provides previously unseen structure of telomere-controlling enzyme.