In results presented at the American Association for Cancer Research (AACR) Annual Meeting 2015, a collaborative study by the University of Colorado and the National Cancer Institute (NCI) reports that … Continue Reading Precision medicine study shows the most frequently altered gene in bladder cancer.
The first-ever systematic study of the genomes of patients with ALK-negative anaplastic large cell lymphoma (ALCL), a particularly aggressive form of non-Hodgkin’s lymphoma, shows that many cases of the disease … Continue Reading Researchers demystify rare, deadly lymphoma.
Genetic studies in humans, zebrafish and mice have revealed how two different types of genetic variations team up to cause a rare condition called Hirschsprung’s disease. The findings from Johns … Continue Reading Researchers identify new genetic variants in Hirschsprung’s disease development.
A small number of children who catch the influenza virus fall so ill they end up in the hospital, perhaps needing ventilators to breathe, even while their family and friends … Continue Reading Epigenetic mutation helps explain why, in rare cases, flu can kill.
A research team at UC San Francisco has discovered an RNA molecule called Pnky that can be manipulated to increase the production of neurons from neural stem cells. The opensource … Continue Reading Researchers identify noncoding RNA crucial for stem cell suppression in the brain.
In the battle between a cell and a virus, either side may resort to subterfuge. Molecular messages, which control the cellular machinery both sides need, are vulnerable to interception or … Continue Reading Researchers map microRNA’s role in the human hepatitis c infection.
In 1953 Watson and Crick first published the discovery of the double helix structure of the DNA. They were able to visualize the DNA structure by means of X-Ray diffraction. … Continue Reading Researchers image and count nucleosomes in the human genome for the first time ever.
Researchers from the NYU Langone Medical Center and New York University have demonstrated that a specialized DNA-binding protein called CTCF is essential for the precise expression of genes that control … Continue Reading Researchers identify specialized protein crucial for normal neurodevelopment.
A study led by researchers from the University of Toronto and the Centre for Genomic Regulation has described a group of small DNA fragments that are key in neuron regulation … Continue Reading Neurogenetics study detects and identifies the function of microexons for the first time.
Researchers at the University of Connecticut have found a new way to identify protein mutations in cancer cells. The novel method is being used to develop precision medical vaccines to treat … Continue Reading Researchers develop first individualised precise medical vaccine for ovarian cancer.
Researchers have encountered variants or isoforms in microRNAs (miRNAs) before, but assumed that these variants were accidental byproducts. A recent study from Thomas Jefferson University shows that certain so called … Continue Reading Researchers begin to map function and expression of isomiRs of microRNA.
Over the years researchers have made tremendous strides in the understanding and treatment of cancer by searching genomes for links between genetic alterations and disease. Most of those studies have … Continue Reading Penn team mine specific ovarian cancer oncogene in ‘junk DNA’.
Howard Hughes Medical Institute (HHMI) scientists have developed a strategy for finding disease-causing mutations that lurk in only a small fraction of the body’s cells. Such mutations can cause significant … Continue Reading New gene technique identifies hidden causes of brain malformation.
Scientists from the Northwestern University have identified a biomarker strongly associated with basal-like breast cancer, a highly aggressive carcinoma that is resistant to many types of chemotherapy. The biomarker, a … Continue Reading Biomarker in an aggressive breast cancer is identified.
A new study from the University of Lubeck identifies a novel gene that controls nerve conduction velocity. Investigators report that even minor reductions in conduction velocity may aggravate disease in multiple … Continue Reading Gene that controls nerve conduction velocity linked to multiple sclerosis.
The U.S. Food and Drug Administration has approved Cologuard, the first stool-based colorectal screening test that detects the presence of red blood cells and DNA mutations that may indicate the … Continue Reading FDA approves world’s first non-invasive DNA screening test for colorectal cancer.