Type I diabetes is a disease with two parts, firstly, the beta cells are killed by the body’s own immune system, and then secondly they fail to regenerate, causing the … Continue Reading Previously unknown type of regenerating insulin-producing cell discovered.
Vital to our bodies, preproglucagon otherwise known as GCG peptides act in both the periphery and the CNS to change food intake, glucose homeostasis, and metabolic rate. Although the actions … Continue Reading Neurons successfully regulate appetite and glucose levels in mice.
Several healthinnovations or disruptive technologies can be identified that might, at some point in the future, displace established laboratory medicine technologies and practices. One of these highly desirable technologies is … Continue Reading Researchers report the invention of glucose-sensing contact lens.
About 8% of Americans have type 2 diabetes, and another 25% of the population is at risk because of obesity. Type 2 diabetes is a lifelong disease that represents an … Continue Reading Study identifies new pathway in insulin resistance.
The autonomic nervous system, made up of sympathetic and parasympathetic branches, is known to regulate blood glucose levels by directly controlling insulin secretion by the pancreas. Insulin secretion and blood … Continue Reading Hormone inhibits neuronal connections between the brain and pancreas in neurodevelopment.
A large body of data gathered over the last decades has identified the neuronal pathways which link the central nervous system with the autonomic innervation of the endocrine pancreas. These … Continue Reading Study shows brain cell mitochondria controls blood-sugar levels after a meal.
It is known that diabetes is a disease that commonly inflicts the pancreas, the organ responsible for insulin production. More specifically, it inflicts the cells that produce insulin, which are … Continue Reading Researchers identify a previously unknown developmental cause of diabetes.
Type 1 diabetes is the autoimmune form of diabetes, in which insulin-producing beta cells in the pancreas are destroyed by immune cells, especially those known as T cells. Insulin is … Continue Reading Researchers identify previously unknown class of antigen present in T1 diabetes.
Type 2 diabetes is a chronic illness characterised by the presence of elevated blood glucose levels. It accounts for between 80 and 90% of diabetes cases and is one of … Continue Reading Large-scale study identifies an epigenetic marker for Type 2 diabetes.
Glucose-stimulated insulin secretion (GSIS) in pancreatic beta cells maintains glucose homeostasis and prevents diabetes. Despite decades of studies, knowledge about what controls the precise amount of insulin release on a … Continue Reading Researchers identify microtubule mechanism and role in insulin secretion.
In comparison to other organs, the human brain has the highest energy requirements. The supply of energy for nerve cells and the particular role of lactic acid (lactate) has been … Continue Reading Study confirms 20 year-old hypothesis on the brain using lactate for energy.
All mammals, including humans, have two types of fat with completely opposite functions. These are white fat, which stores energy and is linked with diabetes and obesity; and brown fat, … Continue Reading Researchers identify epigenetic switch which generates calorie-burning brown fat.
Diabetes is a lifelong condition caused by a deficiency in the ability to make insulin, a hormone that regulates glucose levels. According to the Center for Disease Control, diabetes affects … Continue Reading Oral formulation of insulin successful in animal model.
High blood sugar is a defining characteristic of Type 2 diabetes and the cause of many of the condition’s complications, including kidney failure, heart disease, and blindness. Most diabetes medications … Continue Reading Researchers block mitochondrial glucose production to treat type 2 diabetes in preclinical trials.
Impaired activation of mitochondrial energy metabolism in the presence of glucose has been demonstrated in pancreatic beta-cells from patients with type 2 diabetes. The cause of this dysfunction has been … Continue Reading New diagnostic identifies mitochondria dysfunction in Type 2 diabetes.
Practically everyone gets fatter as they get older, however, according to a new study from researchers at Duke University some people can blame their genes for the extra padding. The … Continue Reading Researchers identify gene responsible for obesity and diabetes in old age.