Tag Archives: glutamatergic

Study implicates two genes in the cause of schizophrenia, vital for signalling balance.


In the mammalian central nervous system, neurons receive inhibitory synaptic inputs from gamma-aminobutyric acid (GABA)ergic interneurons and excitatory inputs from glutamatergic neurons. Evidence suggests that the dysfunction of appropriate GABAergic inhibition and the consequent imbalance between excitation and inhibition in the cerebral cortex underlie the cause of schizophrenia. Now, a study from researchers at Duke-NUS Graduate Medical School Singapore (Duke-NUS)

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