Epigenetic dysfunction is implicated in many neurological and psychiatric diseases, including Alzheimer’s disease and schizophrenia. Consequently, histone deacetylases (HDACs) are being aggressively pursued as therapeutic targets. However, a fundamental knowledge … Continue Reading Researchers image the epigenetics of the human brain for the first time ever.
Epigenetics is a research field where DNA methylation or histone acetylation, as opposed to the DNA sequence, are studied as a tool for conveying traits to the next generation. Previously, … Continue Reading New type of epigenetic mark identified in the human cell nucleus.
Epigenetics is a process whereby environmental factors can affect DNA and the mechanism by which DNA is transcribed and translated into proteins. Epigenetic regulation has been observed to affect a … Continue Reading Researchers reprogram social behaviour in carpenter ants using epigenetic drugs.
Herpes simplex virus (HSV) is found in the brain cells of approximately 90% of the world’s population and leads to cold sores, recurrent eye infections, genital lesions, and in rare … Continue Reading Study shows how the herpes simplex virus reactivates in neurons.
Antigen receptor genes are assembled by controlled, large-scale deletions and inversions. Errors in this process, known as V(D)J recombination, produce aberrant genomic rearrangements, which can fuel the development of T- … Continue Reading Researchers identify points where incorrect immune cell DNA editing causes blood cancer.
After it is transcribed from DNA, RNA can go on to many fates. While the most familiar path may lead directly to the production of protein, RNA molecules themselves can … Continue Reading Researchers unlock another piece of the RNA sequencing puzzle.
Researchers at the University of Illinois have identified a molecular mechanism that directs embryonic stem cells to mature into endothelial cells, the specialized cells that form blood vessels. Understanding the … Continue Reading Researchers begin to map the epigenetics that turn stem cells into blood vessel cells.
One of the major challenges of cocaine addiction is the high rate of relapse after periods of withdrawal and abstinence. Now, new research from McGill University and Bar Ilan University reveals … Continue Reading Study shows most epigenetic changes happen in cocaine addiction during the periods of withdrawal.
Epigenetic signals help determine which genes are activated at which time in a given cell. A novel analytical method enables systematic characterization of the relevant epigenetic tags, and reveals that … Continue Reading Scientists begin to hone Precision Epigenetics.