Tag Archives: histone

Researchers image the epigenetics of the human brain for the first time ever.

Epigenetic dysfunction is implicated in many neurological and psychiatric diseases, including Alzheimer’s disease and schizophrenia. Consequently, histone deacetylases (HDACs) are being aggressively pursued as therapeutic targets. However, a fundamental knowledge gap exists regarding the expression and distribution of HDACs in healthy individuals for comparison to disease states.  Now, a study from researchers at Massachusetts General Hospital images, for the first

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