Irreversible degeneration of the cardiac conduction system is a common disease with high rates of mortality. While electronic pacemakers provide effective treatment, alternative approaches are needed with long-term implanted hardware … Continue Reading Extensive lit review performed on harnessing stem cells to generate biological pacemakers.
In the field of iPS cell-based regenerative medicine, advanced research with clinical applications for many organs and tissues, such as the retina, has steadily progressed. However, growing a kidney from … Continue Reading Human stem cell-derived kidneys connect to blood vessels when transplanted into mice.
Aging is a major risk factor for many human diseases, and in vitro generation of human neurons is an attractive approach for modeling aging-related brain disorders. While aggressive familial early … Continue Reading New technique enables researchers to grow old human brain cells for the first time.
The heart is arguably the hardest working muscle in the human body and without its incessant, regular beating the body’s organs would be starved of life-giving nutrients. Yet how the … Continue Reading Researchers identify precision medicine for the development of healthy heart muscle.
A new study from researchers at the IRCM sheds light on a mechanism affecting AID, a crucial enzyme for the immune response. The scientific breakthrough could eventually improve the way … Continue Reading Researchers identify mechanism to control enzyme crucial for boosting immunity.
In a new study from Saint Louis University, researchers discovered that drugs targeting the A3 adenosine receptor can turn off pain signals in the spinal cord to provide relief from … Continue Reading Researchers use A3 adenosine receptors to activate ‘off signals’ for chronic pain.
An injection of stem cells into the eye may soon slow or reverse the effects of early-stage age-related macular degeneration, according to new research from scientists at Cedars-Sinai. Currently, there … Continue Reading Stem cell injection reverses vision loss due to age-related macular degeneration in animal model.
Researchers show for the first time that mitochondria are altered in human model of Parkinson’s disease.
It has long been suspected that the most common mutation linked to both sporadic and familial Parkinson’s disease wreaks its havoc by altering the function of mitochondria in neurons that … Continue Reading Researchers show for the first time that mitochondria are altered in human model of Parkinson’s disease.
For infants with severe combined immunodeficiency (SCID), something as simple as a common cold or ear infection can be fatal. Born with an incomplete immune system, kids who have SCID, … Continue Reading Researchers grow and correct an SCID immune system in-a-dish via precision medicine.
New precision medicine ‘edits’ sickle cell gene and allows researchers to regrow normal blood cells.
Researchers at Johns Hopkins have successfully corrected a genetic error in stem cells from patients with sickle cell disease, and then used those cells to grow mature red blood cells, … Continue Reading New precision medicine ‘edits’ sickle cell gene and allows researchers to regrow normal blood cells.
Medical marijuana is proliferating across the country due to the ability of cannabis ingestion to treat important clinical problems such as chronic pain. However, negative side effects and the development … Continue Reading Cannabinoid CB2 receptors suppress neuropathic pain with no signs of physical dependence in study.
Researchers have for the first time successfully converted adult human skin cells into neurons of the type that regulate appetite, providing a patient-specific model for studying the neurophysiology of weight … Continue Reading In world’s first researchers differentiate skin cells into neurons controlling appetite.
In a study that provides scientists with a critical new understanding of stem cell development and its role in disease, UCLA researchers have established a first-of-its-kind methodology that defines the … Continue Reading Scientists develop method to define, standardise stages of stem cell reprogramming.
Researchers from KU Leuven have identified a new strategy for treating an inherited form of dementia after attempting to turn stem cells derived from patients into the neurons most affected … Continue Reading Patient stem cells used to make dementia-in-a-dish for the first time.
Researchers at the Weizmann Institute of Science and Cambridge University have jointly managed the feat of turning back the clock on human cells to create primordial germ cells, the embryonic … Continue Reading Human primordial cells programmed in the lab for the first time.
Mouse cells and tissues created through nuclear transfer can be rejected by the body because of a previously unknown immune response to the cell’s mitochondria, according to an international study … Continue Reading Previously unseen immune reaction identified for stem cell transplants.