A worldwide rise in immune and inflammatory diseases such as multiple sclerosis and inflammatory bowel diseases has been linked to Western society-based changes in lifestyle and environment. These include decreased … Continue Reading Sunlight affects the gut microbiota and vitamin D levels.
Highly painful in nature, inflammatory bowel diseases (IBD) consisting of Crohn’s and ulcerative colitis are caused by dysregulation of the immune system leading to intestinal inflammation and microbial changes. Numerous … Continue Reading Metabolite produced by gut microbiota from pomegranates reduces inflammatory bowel disease.
Crohn’s disease, a common inflammatory disorder of the intestinal tract, can have devastating consequences for a patient’s quality of life. Although people with the disease are typically treated with powerful … Continue Reading Researchers identify 2 distinct genetic subtypes in Crohn’s disease patients.
It is known that patients with Crohn’s disease have uncontrolled inflammation in their gut, which can lead to intestinal fibrosis and narrowing that can slow or block the movement of … Continue Reading Study identifies immune cells critical for the development of fibrosis in Crohn’s disease.
The inflammatory response is an integral part of the innate immune mechanism that is triggered in response to a real or perceived threat to tissue homeostasis, with a primary aim … Continue Reading New class of molecule identified in central role of inflammation and the immune system.
There is a clinical need for new, more effective treatments for chronic and debilitating inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis. Now, a study from researchers at … Continue Reading Plant-based nanoparticles successfully treat inflammatory bowel disease in animal model.
Patients suffering from so-called immune-mediated neuropathies frequently have a long medical record. As there are no diagnostic tests available to reliably diagnose the disease, the diagnosis is frequently made belatedly … Continue Reading Study identifies previously unknown cause of immune neuropathy.
The need for a new approach to treat Alzheimer’s is an urgent priority for governments across the globe. It is the most common age-related dementia, and the number of people … Continue Reading Gamechanging human study identifies 3 distinct subtypes of Alzheimer’s disease.
Inflammatory bowel disease (IBD) is a painful, chronic inflammation of the gastrointestinal tract, affecting roughly two million children and adults in the U.S. Inflammatory bowel disease (IBD) beginning in childhood tends … Continue Reading Study identifies gene variants in inflammatory bowel disease under Age 5.
First comprehensive study of genetic risks for Inflammatory Bowel Disease (IBD) in African-Americans performed.
Crohn’s disease and ulcerative colitis are chronic autoimmune diseases that affect as many as 1.6 million Americans. Patients with Inflammatory Bowel Disease (IBD) have immune systems that attack their own … Continue Reading First comprehensive study of genetic risks for Inflammatory Bowel Disease (IBD) in African-Americans performed.
To be activated, T cells must first recognize an antigen, receive appropriate costimulatory signals, and then encounter inflammatory cytokines to expand the immune response. This immune response has been harnessed … Continue Reading New T-cell regulation discovery set to rewrite immunology text books.
The immune system not only responds to infections and other potentially problematic abnormalities in the body, it also contains a built-in brake in the form of regulatory T cells. These … Continue Reading Researchers identify a previously unknown regulator of the immune system.
There is currently great interest in treating ulcerative colitis with fecal microbiota transplantation (FMT), which involves transplanting gut fecal bacteria from healthy people into patients with ulcerative colitis. Now, two new … Continue Reading First ever trial of fecal microbiota transplantation in humans with ulcerative colitis successful.
Metabolism experts are increasingly convinced that obesity and many of the pathogenic changes it entails, such as Metabolic Syndrome and type 2 diabetes, are a result of chronic inflammatory processes … Continue Reading Researchers identify enzyme in animal model responsible for metabolism disorders due to obesity.
A drug that could halt the progression of multiple sclerosis may soon be developed thanks to a discovery by a team at the CHUM Research Centre and the University of … Continue Reading New treatment blocks progression of mutliple sclerosis in animal model.
Microbes in the human body are estimated to outnumber human cells by 10 to 1, yet research on how they affect health is still in its infancy. A perspective article … Continue Reading Swallowable gas capsule could be used to measure intestinal gas to diagnose disease.