In patients with diabetes, the immune system attacks the pancreas, eventually leaving patients without the ability to naturally control blood sugar. These patients must carefully monitor the amount of sugar … Continue Reading Living drug factories can be implanted to produce insulin for months.
Researchers have long explored ways to transplant pancreatic islets to treat type I diabetes in the long term to eliminate the need for continuous glucose monitoring and insulin injections. However, … Continue Reading Tiny drug-delivering capsules could sustain transplanted insulin-producing cells.
Type I diabetes is a disease with two parts, firstly, the beta cells are killed by the body’s own immune system, and then secondly they fail to regenerate, causing the … Continue Reading Previously unknown type of regenerating insulin-producing cell discovered.
It is known that insulin resistance is present long before the onset of type 2 diabetes and results not only from genetics and lifestyle factors but likely also from environmental … Continue Reading Large-scale study shows that air pollution raises type 2 diabetes risk.
Diabetes is a chronic condition that causes high blood sugar levels that are potentially fatal if left unmanaged. Injection of insulin is the primary treatment against this disease. Unfortunately a … Continue Reading New insulin pill successful in animal studies.
About 8% of Americans have type 2 diabetes, and another 25% of the population is at risk because of obesity. Type 2 diabetes is a lifelong disease that represents an … Continue Reading Study identifies new pathway in insulin resistance.
It is known that genetics plays a role in obesity, with genes directly causing obesity in disorders such as Bardet-Biedl syndrome and Prader-Willi syndrome. However, genes and behaviour may both … Continue Reading Human study shows ‘aggressive drunk’ gene may protect carriers from obesity and associated risks.
Obesity is a global health problem that poses a major risk factor for life-threatening diseases such as cardiovascular disease, cancer, and neurodegeneration. Recent studies have identified specific loci associated with … Continue Reading Study maps a molecular link between insulin-sensitivity and obesity.
It is known that the loss or dysfunction of islet β cells in the pancreas results in an imbalance in blood glucose homeostasis, leading to the development of type 2 … Continue Reading Researchers identify new links between nicotine and type 2 diabetes.
It is known that cardiac natriuretic peptides (NPs) are hormones produced by the heart to influence blood pressure. When the heart senses elevated pressure, it releases NPs, which go to the … Continue Reading Human study identifies link between heart hormones, obesity, and diabetes.
It is known that diabetes is a disease that commonly inflicts the pancreas, the organ responsible for insulin production. More specifically, it inflicts the cells that produce insulin, which are … Continue Reading Researchers identify a previously unknown developmental cause of diabetes.
Type 1 diabetes is the autoimmune form of diabetes, in which insulin-producing beta cells in the pancreas are destroyed by immune cells, especially those known as T cells. Insulin is … Continue Reading Researchers identify previously unknown class of antigen present in T1 diabetes.
Metabolism is the process by which the human body converts caloric intake into energy. A number of factors determine the amount of calories burnt, namely caloric intake, physical activity, as … Continue Reading Researchers identify previously unknown link between stress and fat metabolism.
Glucose-stimulated insulin secretion (GSIS) in pancreatic beta cells maintains glucose homeostasis and prevents diabetes. Despite decades of studies, knowledge about what controls the precise amount of insulin release on a … Continue Reading Researchers identify microtubule mechanism and role in insulin secretion.
Diabetes is a lifelong condition caused by a deficiency in the ability to make insulin, a hormone that regulates glucose levels. According to the Center for Disease Control, diabetes affects … Continue Reading Oral formulation of insulin successful in animal model.
Glutamate is an amino acid with very different functions. In the pancreas, it modulates the activity of the pancreatic ß-cells responsible for insulin production, whereas in the brain it is … Continue Reading Study verifies long-standing hypothesis that glutamate is brain’s energy-source.