Systemic lupus erythematosus (SLE) is a common autoimmune disorder in which the body’s immune system mistakenly attacks healthy tissues, it can affect the skin, joints, kidneys, brain, and other organs. … Continue Reading Study shows how mitochondria drives autoimmune response in lupus.
A main barrier to immune therapy success has been the tumour’s ability to keep the immune system from functioning against the cancer. The immune cells are there, however, like an … Continue Reading Researchers use ‘demethylating’ precision medicine to fight cancer.
Tuberculosis is caused by the bacterium Mycobacterium tuberculosis and it affects over 12 million people globally. When the bacterium infects a person, the body’s immune response is critical to how … Continue Reading Researchers identify how tuberculosis uses precision medicine to trick the immune system.
Researchers have found that an antiviral compound may protect the brain from invading pathogens. Studying West Nile virus infection in mice, researchers at Washington University showed that interferon-lambda tightens the … Continue Reading Researchers ‘block’ the West Nile virus out of the brain by tightening the blood-brain barrier.
A new study led by investigators at Brigham and Women’s Hospital (BWH) reports the discovery of a genetic variant that is associated with a patient’s likelihood of responding to interferon-beta, … Continue Reading New gene identified in multiple sclerosis disease activity.
Human DNA accumulates damage over time, and older people’s bodies can’t repair it as well. Many scientists believe a build up of damage can cause cells to enter an irreversible … Continue Reading Study identifies molecular link between DNA damage and premature aging.
A small number of children who catch the influenza virus fall so ill they end up in the hospital, perhaps needing ventilators to breathe, even while their family and friends … Continue Reading Epigenetic mutation helps explain why, in rare cases, flu can kill.
One of the roadblocks to the eradication of tuberculosis (TB) is the difficulty in identifying patients with latent TB infections. Neither the tuberculin skin test nor interferon-gamma release assays (IGRAs) … Continue Reading New whole blood assay is the first to identify latent TB infections.
Walter and Eliza Hall Institute researchers have for the first time revealed how dying cells are hidden from the immune ‘police’ that patrol the body. The research answers a decades-old … Continue Reading Decades-old mystery about the death of cells uncovered by scientists.