A devastating disease, childhood leukemia, the most prevalent type of cancer in children and teens, is a cancer of the body’s immune cells, also known as white blood cells. Abnormal … Continue Reading Human immune cells in-a-dish produced in world’s first.
Leukemia, or blood cancer, involves pathological alterations in the body’s hematopoietic system. In acute myeloid leukemia, it is specifically the bone marrow that is affected. In a healthy body, different … Continue Reading Previously unknown cell-death pathway mapped in leukemia cells.
Multiple myeloma, also known as myeloma, is a type of bone marrow cancer. Multiple myeloma affects the plasma cells, blood cell, inside the bone marrow. Myeloma does not take the form of a … Continue Reading Study is first to link multiple myeloma protein to extramedullary disease.
ALL is identified in about 3,000 individuals each year aged 19 or younger in the U.S., making it the most common childhood cancer. While the cause remains largely unknown, only … Continue Reading Researchers identify inherited gene variation linked to greater acute lymphoblastic leukemia risk.
To better understand diseases with a genetic component, a popular approach is to take skin cells from patients with a disease and use enzymes to coax the cells back along … Continue Reading Researchers successfully develop leukemia-in-a-dish.
Chromosomal alterations and deletions are often observed in cancers. Recurrent genetic losses are thought to contribute to disease processes through deregulating critical cellular programs that govern proliferation and differentiation. However, … Continue Reading Researchers identify precision medicine, suppressor gene for acute myeloid leukemia.
University of California San Francisco scientists have identified characteristics of a family of daughter cells, called MPPs, which are the first to arise from stem cells within bone marrow that … Continue Reading Reseachers identify and map progenitor cells for blood and immune cell production.
Research led by the University of Michigan has identified a gene critical to controlling the body’s ability to create blood cells and immune cells from blood-forming stem cells, known as … Continue Reading Researchers identify a new gene critical to creating blood cells.
Researchers at the Stanford University have discovered that when a certain aggressive leukemia is causing havoc in the body, the solution may be to force the cancer cells to grow … Continue Reading Researchers engineer a ‘cancer differentiation therapy’ for leukemia.
A new study of acute lymphoblastic leukemia (ALL), a blood cancer that primarily affects young children, has revealed that the disease has two distinct subtypes, and provides preliminary evidence that … Continue Reading Precision medicine study reveals new subtype of childhood leukemia.
Researchers identify gene mutation that raises risk of nerve damage in leukemia patients using Vincristine.
Researchers from St. Jude Children’s Research Hospital have identified the first genetic variation that is associated with increased risk and severity of peripheral neuropathy following treatment with a widely used … Continue Reading Researchers identify gene mutation that raises risk of nerve damage in leukemia patients using Vincristine.
A University of Colorado study published in the journal Stem Cells has identified a program that makes stem cells damaged by radiation differentiate into other cells that can no longer … Continue Reading Researchers reprogram stem cells after radiation, lower cancer risk.
The genetic tumult within cancerous tumours is more than matched by the disorder in one of the mechanisms for switching cells’ genes on and off, scientists at Dana-Farber Cancer Institute … Continue Reading Disorder in epigenetics is a defining characteristic of cancer.
Researchers at Children’s Hospital Los Angeles have shown that a select team of immune-system cells from patients with leukemia can be multiplied in the lab, creating an army of natural … Continue Reading Natural (born) killer cells battle pediatric leukemia.
The ability to reliably and safely make in the laboratory all of the different types of cells in human blood is one key step closer to reality. A group from … Continue Reading Wisconsin scientists find genetic recipe to turn stem cells to blood.