Our immune system, consisting of proteins, microbes, and specialized immune cells known as white blood cell cells, is crucial for survival. Macrophages are a white blood cell engulfing and destroying … Continue Reading Newly discovered lung-only immune cells may have implications for coronavirus.
Sepsis is the overreaction of the body’s immune system to infection capable of causing tissue damage, organ failure, and death. Sepsis-causing bacteria secrete toxic molecules known as endotoxins which trigger immune … Continue Reading Engineered macrophage nanosponges could keep sepsis in check.
Angiogenesis, the growth of new blood vessels from pre-existing ones, is required for wound healing, menstruation, embryogenesis and various pathological conditions including tumour growth. Macrophages, key cells of the innate … Continue Reading Immune cells shown to facilitate tumour growth by forming primitive vascular channels.
Previously unknown immune cell identified, which protects against lung infections during chemotherapy.
It is known that chemotherapy drugs kill dividing cells, including cells in the bone marrow that give rise to different immune cells. However, this can lead to a dramatic reduction … Continue Reading Previously unknown immune cell identified, which protects against lung infections during chemotherapy.
Macrophages, also known as scavenger cells, are immune cells which are part of the innate immune system and differentiate from monocytes. They circulate in the bloodstream and upon differentiation, invade … Continue Reading New study refutes textbook theory on macrophage metabolism.
It is known that HIV, the causative agent of AIDS, is severely species restricted, and, to date, only humans and chimpanzees have been shown to be susceptible to infection. Human … Continue Reading First-ever study proves HIV targets & replicates in human macrophages.
The peripheral nervous system is a vast network of nerves that exists primarily outside of brain and spinal cord and connects to the far reaches of the body. The very … Continue Reading Study shows how protein promotes regeneration of injured peripheral nerves.
Worldwide, more than 20% of persons over the age of 85 suffer from Alzheimer’s disease. Deposits of beta-amyloid (Aβ) peptide represent an important target for research into Alzheimer’s disease. These … Continue Reading Researchers take a step towards utilising the brain’s microglia to fight Alzheimer’s disease.
Tuberculosis is caused by the bacterium Mycobacterium tuberculosis and it affects over 12 million people globally. When the bacterium infects a person, the body’s immune response is critical to how … Continue Reading Researchers identify how tuberculosis uses precision medicine to trick the immune system.
New research by researchers at the University of Massachusetts suggests the immune system plays an unsuspected and surprising role in the progression of Rett syndrome, a severe neurological disorder affecting … Continue Reading Researchers identify the role of microglia in Rett syndrome.
Despite symptom-stifling anti-retroviral drugs, as many as half of all patients living with HIV experience neurological damage tied to chronic inflammation in the brain fueled by the body’s own immune … Continue Reading Study discovers the role of microglia in HIV-related neurological damage.
Researchers at the University of North Carolina have used exosomes, tiny bubbles of protein and fat produced naturally by cells, to bypass the body’s defenses and deliver a potent antioxidant … Continue Reading Researchers utilize natural exosomes to deliver Parkinson’s treatment directly to brain.
A research team showed that a nanotherapeutic medicine can halt the growth of artery plaque cells resulting in the fast reduction of the inflammation that may cause a heart attack, … Continue Reading Nanotechnology successfully used to halt atherosclerotic plaque growth in animal model.
A group of researchers from Washington University, Agios Pharmaceuticals and ITMO University has discovered new metabolic mechanisms that regulate macrophage polarization, the unique ability of these immune cells to change … Continue Reading Epigenetic metabolic pathways mapped that regulate the macrophage’s role in immune response.
Researchers at the Stanford University have discovered that when a certain aggressive leukemia is causing havoc in the body, the solution may be to force the cancer cells to grow … Continue Reading Researchers engineer a ‘cancer differentiation therapy’ for leukemia.
Novel nanoparticle enables MRI to visualize pancreas inflammation in T1 diabetes for the first time.
A pilot study led by researchers at the Joslin Diabetes Center and the Massachusetts General Hospital have revealed that it is possible to use magnetic resonance imaging (MRI) to image … Continue Reading Novel nanoparticle enables MRI to visualize pancreas inflammation in T1 diabetes for the first time.