Multiple myeloma, also known as myeloma, is a type of bone marrow cancer. Multiple myeloma affects the plasma cells, blood cell, inside the bone marrow. Myeloma does not take the form of a … Continue Reading Study is first to link multiple myeloma protein to extramedullary disease.
Unprecedented precision study identifies the four genes responsible for blood stem cell development.
Every day, over 100 billion new mature blood cells are generated in an adult human. This major production places high demands on the blood stem cells which must be capable … Continue Reading Unprecedented precision study identifies the four genes responsible for blood stem cell development.
While all red and white blood cells derive from stem cells in the bone marrow, the scientific community has been divided as to whether bone marrow cells are also able … Continue Reading Long-term study uncovers previously unknown mechanism of the formation of fat tissue in humans.
Diabetic neuropathy is a condition in which perpetually high blood sugar causes nerve damage, resulting in a myriad of symptoms such as numbness, reduced ability to detect painful stimuli, muscle … Continue Reading Stem cell injections improve diabetic neuropathy in animal models.
In a report on what is believed to be the first small clinical trial of its kind, researchers at the Johns Hopkins Kimmel Cancer Center say they have safely used … Continue Reading Researchers safely use immune cells to treat multiple myeloma in human trials.
A novel blood test could greatly improve triage of victims of radiation accidents by rapidly predicting who will survive, who will die, and who should receive immediate medical countermeasures, according … Continue Reading New RNA-based blood test quickly reveals severity of radiation injury.
Telomeres are short stretches of repeated nucleotides that protect the ends of chromosomes. In somatic cells, these protective sequences become shorter with each cellular replication until a critical length is … Continue Reading Large scale human study shows longer telomere length leads to higher cancer mortality.
Scientists at the University of California, Berkeley, have identified a new molecular pathway critical to aging, and confirmed that the process can be manipulated to help make old blood like … Continue Reading Researchers identify new mitochondrial pathway critical to aging.
Healthy bone is continuously involved in a dynamic process that includes bone deposition and bone resorption. However, when a person has cancer that spreads to the bone and bone marrow, … Continue Reading Researchers identify new role for cytokine VEGFA in the metastasis of neuroblastoma.
Columbia University Medical Center (CUMC) researchers have pinpointed the immune system mechanism that allows a kidney transplant to be accepted without lifelong immunosuppressive drugs, a significant step toward reducing or … Continue Reading Kidney transplant tolerance mechanism identified.
For infants with severe combined immunodeficiency (SCID), something as simple as a common cold or ear infection can be fatal. Born with an incomplete immune system, kids who have SCID, … Continue Reading Researchers grow and correct an SCID immune system in-a-dish via precision medicine.
New precision medicine ‘edits’ sickle cell gene and allows researchers to regrow normal blood cells.
Researchers at Johns Hopkins have successfully corrected a genetic error in stem cells from patients with sickle cell disease, and then used those cells to grow mature red blood cells, … Continue Reading New precision medicine ‘edits’ sickle cell gene and allows researchers to regrow normal blood cells.
UCLA scientists have for the first time identified a protein that plays a key role in regulating how blood stem cells replicate in humans. This discovery lays the groundwork for … Continue Reading Researchers identify key regulating protein in human blood stem cell replication.
The ‘molecular mail’ sent by multiple myeloma cells provides clues to how well patients with the disease are likely to respond to treatment, according to a study being presented at … Continue Reading Researchers use circulating RNA to provide multiple myeloma prognosis.