Saturated fat in red meat has long been linked to a raised risk of heart disease, with TMAO (trimethylamine N-oxide), a gut microbiota-generated metabolite, also linked to the pathogenesis of … Continue Reading Chronic red meat consumption alters gut microbiota, raises heart disease risk.
A decades-long raging epidemic, obesity has been shown to increase the risk of non-alcoholic fatty liver disease (NAFLD)in at least 30% of obese children, leading to liver failure requiring a … Continue Reading Alterations in infant microbiota linked to childhood obesity and liver disease.
Approximately half the adult population in the United States is suffering from back or neck pain whose treatment and care costs result in an estimated 195 billion USD a year. … Continue Reading Spinal discs made of engineered living tissue implanted in large animal model.
In the film, Jurassic Park scientists revive dinosaurs by extracting DNA from drops of blood fossilized within insects trapped in amber. They then decode the genetic sequence, fill in gaps … Continue Reading Synthetic biology used to de-extinct plants to manufacture perfume.
The origins of life on earth have been a fascination for researchers and the public alike for many years. To date, researchers have traced the arc of life back several … Continue Reading Synthetic microorganisms allow researchers to study billion-year-old evolutionary mysteries.
According to human anatomy, the ligaments in the ankle are grouped by two ligament complexes, namely the lateral collateral ligament and the medial collateral ligament. The ankle lateral collateral ligament … Continue Reading Researchers discover a new anatomic structure in the ankle.
In evolutionary biology, protocells are thought to be a stepping-stone to the origin of life, hypothesized as the first cells to transfer genetic information via RNA before the onset of … Continue Reading Researchers develop synthetic prototissue capable of synchronized beating.
Astrocytes are the most abundant glial cells in the central nervous system (CNS) known to be involved in many roles in the brain including the composition of the blood-brain barrier, … Continue Reading Astrocytes found to have a direct role in brain plasticity.
In the course of evolution, nature has produced thousands of enzymes to facilitate the myriad of chemical reactions taking place inside living organisms every day. Enzymes are responsible for accelerating … Continue Reading Researchers develop an artificial enzyme that speeds reactions in living cells.
The human skeleton is an amalgam of diverse tissue types including bone, cartilage, and fat cells. Each tissue type in the skeleton is generated and maintained by the precise regulation … Continue Reading Researchers identify elusive human skeletal stem cells.
Tooth loss is a major public health issue affecting more than 158 million people worldwide. The current standard of care is to replace missing teeth with synthetic dental implants, and/or … Continue Reading Researchers successfully implant and innervate bioengineered teeth derived from postnatal cells.
In many cases, oral administration is the preferred method of drug delivery, with formulation of nanoparticles shown to improve drug stability in the harsh gastrointestinal (GI) tract environment. However, diverse … Continue Reading Study provides proof-of-concept for the oral delivery of nanoparticles.
Synthetic biology involves the fabrication of previously non-existent biological components and systems, consisting of quickly manufactured DNA sequences assembled into new genomes. The main goal of synthetic biology is the … Continue Reading Synthetic tissues build and regenerate themselves.
The enteric nervous system (ENS) is known as the second brain, or the brain in the gut, due to the fact it can operate independently of the central nervous system … Continue Reading Study identifies previously unknown neuronal activity in the gut.
Membrane proteins are a basic component of every cell in the human body, playing a vital role in the cell’s structure, metabolism, and transport. They ensure substances, such as proteins, … Continue Reading New nanosensor can live-track a proteins’ pathway through the cell.
Robots residing inside the body to restore or enhance biological function have long been a hope for the future. Developing such robotic implants poses challenges both in signaling between the … Continue Reading Robotic implants spur tissue regeneration inside the body.