The limited removal of metabolic waste products in dialyzed kidney patients leads to high morbidity and mortality. A bioartificial kidney could replace the need for dialysis or transplantation in the … Continue Reading Researchers develop functional living membrane in massive leap towards a bioartificial kidney.
Lung disease causes more than 200,000 deaths annually in the United States. Although the lung is generally considered slow to respond to disease and injury, it does undergo regenerative processes, … Continue Reading Researchers develop tissue-engineered model of human lung and trachea.
It is known that nerves in the central nervous system of adult mammals do not usually regenerate when injured. However, the granule cell, a nerve cell located in the cerebellum, … Continue Reading Key molecule in the elusive regeneration of cerebellum synaptic connections identified.
Like a magician, the freshwater flatworm known as planaria can survive decapitation or even being cut into many pieces. Its ability to fully regenerate from tiny remnants of tissue is … Continue Reading Elusive key molecular signal for planarian stem cell regeneration identified.
High-density lipoproteins are complex particles composed of multiple proteins which transport fat molecules around the body. High-density lipoprotein particles are sometimes referred to as good cholesterol because they can transport … Continue Reading Human study identifies link between the GALNT2 gene and levels of HDL cholesterol.
It is known that skeletal muscle regeneration is impaired in age-related diseases such as sarcopenia, which is marked by reduced muscle regenerative capacity with aging, due in part to a … Continue Reading Study identifies gene responsible for regeneration of injured muscle by adult stem cells.
It is known that the formation of large numbers of polyps in the colon has a high probability of developing into colon cancer, if left untreated. The large-scale appearance of … Continue Reading Previously unknown gene mutation in hereditary colon cancer identified.
One of the processes associated with aging is progressive shortening of telomeres, DNA-protecting structures at the ends of chromosomes, like the plastic tips on shoelaces. Each time a cell divides, … Continue Reading Male hormone reverses cell aging, increases telomere length, in clinical trial.
Colorectal cancer is the development of cancer from the colon or rectum, due to the abnormal growth of cells that have the ability to invade or spread to other parts … Continue Reading Genetic cause of 15% of all colorectal cancer diagnoses identified.
Charcot-Marie-Tooth Disease (CMT) is a family of inherited disorders of the peripheral nervous system, affecting approximately one in 2,500 Americans. Its most common iteration, CMT1, comes in many forms, most … Continue Reading Researchers identify previously unknown genetic cause of inherited neuropathy.
During exercise, muscle function needs to significantly increase; this requires that the uptake and breakdown of the two main nutrients of myofibers, glucose and fatty acids (FAs), markedly rise. The … Continue Reading First ever bone-derived hormone to affect exercise capacity identified.
Nervous system injuries affect over 90,000 people every year, with spinal cord injuries alone estimated to affect 10,000 people each year. As a result of this high incidence of neurological … Continue Reading Researchers successfully control mitochondria to regenerate damaged neurons.
Heart failure is one of the main health problems worldwide, and the urgent medical needs relating to it have positioned cardiovascular research as one of the most actively evolving fields … Continue Reading Study links adult heart regeneration to telomere length in animal model.
More than 600,000 patients in the United States alone suffer from end-stage liver disease, or cirrhosis. The only available cure is liver transplantation, but the shortage of donor livers means … Continue Reading New approach repairs living liver from within with no need of cell transplants.
Red blood cells are the most abundant cells in the human body, and transport oxygen and carbon dioxide. Millions of people worldwide suffer from anaemia, a condition in which the … Continue Reading Study identifies the genetic code of red blood cells.
Mesenchymal stem cells (MSCs) are among the major stem cells used for cell therapy and regenerative medicine. In-vivo cell-tracking by magnetic resonance imaging (MRI) is crucial for regenerative medicine, allowing … Continue Reading Biomimetic method produces large numbers of MRI-trackable mesenchymal stem cells.