Tails in lizards and arms in starfish show an astounding ability to regrow, however, mammals have partially lost the capacity to extensively regenerate body parts. The liver is unique among … Continue Reading Researchers use epigenetic mechanism to regenerate mammalian liver.
Genetic susceptibility is thought to play a role in common diseases including those affecting the colon such as inflammatory bowel diseases (IBD) and colorectal cancer. As is the case for … Continue Reading Study shows how gut microbiota interact with genes to promote Crohn’s disease.
With Parkinson’s disease clinicians have long noted that the presence of tremors, rather than balance and walking problems is the initial or dominant symptom and hypothesize this may even suggest … Continue Reading Human study identifies genetic variation for type and rate of physical decline Parkinson’s disease.
The human heart is a remarkable muscle, beating more than 2 billion times over the average life span. However, the heart’s efficiency can decrease over time. One major contributor to … Continue Reading Study identifies protein with power to improve heart function.
With type 1 diabetes too much glucose and fat circulating in the blood help make cardiovascular disease the leading cause of death and disability in people with the disease. While … Continue Reading New pathway and potential treatment identified for unhealthy levels of fat in type 1 diabetes.
Coeliac disease is a chronic, immunological disease that is manifested as intolerance to gluten proteins present in wheat, rye and barley. This intolerance leads to an inflammatory reaction in the … Continue Reading Gene crucial to the development of celiac disease found in ‘junk’ DNA.
Research into bioengineering has led to important achievements in recent years, with a number of different tissue types being developed. In the area of skin tissue epithelial cells have been … Continue Reading Researcher successfully grow complex, implantable, skin tissue for the first time.
Type 1 diabetes is an autoimmune disease, meaning that the underlying problem is with the immune system. It is still unclear as to why the body’s immune system attacks and … Continue Reading Salmonella-based oral vaccine for T1 diabetes successful in animal model.
In humans, the surgical removal of an ovary or ovaries is most often performed due to diseases such as ovarian cysts or cancer, or in conjunction with hysterectomy. In the … Continue Reading 3D-printed ovary bioprosthesis restores fertility in mice.
The innate immune system is hard-wired to protect people from infection. However, mutations in these protective genes can lead to uncontrolled inflammation, resulting in autoinflammatory disease. Autoinflammatory diseases are characterized … Continue Reading Precision medicine study identifies decades-old mysterious, rare and debilitating disease.
Pancreatic cancer is a devastating disease, with a death rate close to the incidence rate. Because more than 90% of pancreatic cancer cases are diagnosed at the metastatic stage, when … Continue Reading Early indicators of pancreatic cancer identified in precision medicine study.
The human genome is composed of 20,000 genes and as of today, 3,200 of these genes are known to cause diseases, of which 1,700 are associated with ‘recessive’ diseases. Recessive … Continue Reading Researchers identify a previously unknown neurogenetic recessive disease.
Unprecedented precision study identifies the four genes responsible for blood stem cell development.
Every day, over 100 billion new mature blood cells are generated in an adult human. This major production places high demands on the blood stem cells which must be capable … Continue Reading Unprecedented precision study identifies the four genes responsible for blood stem cell development.
Psoriasis is a chronic autoimmune disorder that affects 2% of the world population. It is characterised by inflammation and scaling of the skin, accompanied by a greater risk of contracting … Continue Reading Researchers identify a link between psoriasis and bone loss.
It is known that HIV, the causative agent of AIDS, is severely species restricted, and, to date, only humans and chimpanzees have been shown to be susceptible to infection. Human … Continue Reading First-ever study proves HIV targets & replicates in human macrophages.
Damage to axons in the central nervous system (CNS) typically results in permanent damage and severed axons in the adult mammalian CNS do not spontaneously regenerate to restore lost functions. … Continue Reading Researchers regenerate damaged nerves via the eye using optogenetics.